Additional file 5 of The Q/R editing site of AMPA receptor GluA2 subunit acts as an epigenetic switch regulating dendritic spines, neurodegeneration and cognitive deficits in Alzheimer’s disease

  • Amanda L. Wright (Creator)
  • Lyndsey M. Konen (Creator)
  • Bruce G. Mockett (Creator)
  • Gary P. Morris (Creator)
  • Anurag Singh (Creator)
  • Lisseth Estefania Burbano (Creator)
  • Luke Milham (Creator)
  • Monica Hoang (Creator)
  • Raphael Zinn (Creator)
  • Rose Chesworth Vieyra (Creator)
  • Richard P. Tan (Creator)
  • Gordon A. Royle (Creator)
  • Ian Clark (Creator)
  • Steven Petrou (Creator)
  • Wickliffe C. Abraham (Creator)
  • Bryce Vissel (Creator)

Dataset

Description

Additional file 5: Sup Figure 5. ADAR2 downregulation. ADAR2 expression is downregulated as shown in immunoassays from (a) J20 mice and (b) 5xFAD mice as compared to WT littermates (t-test = 2.68, p < 0.028; n = 5/genotype; t-test = 2.95, p = 0.021; n’s: WT = 5 and 5xFAD = 4). B shows interpolated blots as well as example electropherograms (EPG) used for analysis. Each value represents the mean ± the SD. *p
Date made available2023
Publisherfigshare

Access Dataset

Cite this