Description
This study seeks to elucidate the benefits of NAC augmentation (2-4 grams/day) compared to placebo in the treatment of OCD, in a 24-week, multi-centre, randomized, double-blind, placebo controlled trial. It is hypothesized that NAC will be superior over placebo for improving OCD symptoms as measured by a reduction in Y-BOCS scores from baseline against each subsequent time point (W4, W8, W12, W16, W20 and W24). Additional benefits are anticipated for relieving anxiety as well as improving mood, functioning and overall quality of life.
The dataset relates to the clinical trial ACTRN12616000847415 N-acetyl cysteine (NAC) augmentation in Obsessive-Compulsive Disorder (OCD): A 24-week, randomized, double blind placebo controlled trial. This data cannot be shared publicly due to ethics approval conditions.
To discuss this data, please contact the NICM Health Research Institute [email protected].
The dataset relates to the clinical trial ACTRN12616000847415 N-acetyl cysteine (NAC) augmentation in Obsessive-Compulsive Disorder (OCD): A 24-week, randomized, double blind placebo controlled trial. This data cannot be shared publicly due to ethics approval conditions.
To discuss this data, please contact the NICM Health Research Institute [email protected].
| Date made available | 1 Apr 2025 |
|---|---|
| Publisher | Western Sydney University |
| Date of data production | 15 Nov 2017 - 30 Jun 2020 |
Research output
- 1 Article
-
N-acetyl cysteine (NAC) augmentation in the treatment of obsessive-compulsive disorder : a phase III, 20-week, double-blind, randomized, placebo-controlled trial
Sarris, J., Byrne, G., Castle, D., Bousman, C., Oliver, G., Cribb, L., Blair-West, S., Brakoulias, V., Camfield, D., Ee, C., Chamoli, S., Boschen, M., Dean, O. M., Dowling, N., Menon, R., Murphy, J., Metri, N.-J., Nguyen, T. P., Wong, A. & Jordan, R. & 4 others, , 13 Jul 2022, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 117, 9 p., 110550.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus)
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