Dr Roland Gamsjaeger is a biochemist/structural biologist. Roland studied chemistry (Master, 2000) and obtained his PhD (fellowship from the Austrian Academy of Sciences, 2005) in the area of biophysics/biochemistry in Austria. He then moved to Australia where he worked as a Schroedinger Postdoctoral Fellow (fellowship from the Austrian Science Fund, 2005-2007) as well as a Postdoctoral Research Associate (2007-2011) in the lab of Prof Joel Mackay at the University of Sydney. During this time his research focused on the structural and biochemical characterisation of proteins involved in transcriptional regulation.

In 2011 Roland joined the University of Western Sydney as a Research Fellow. He is currently a Senior Lecturer in Biochemistry (as well as an honorary Research Fellow at the University of Sydney) involved in the teaching of various units (see Teaching section). His research is centred on viral proteins such as SARS CoV-2 and DNA repair processes (see Research section).

Dr Roland Gamsjaeger has published over 45 research articles and book chapters (with the majority as first, last or corresponding author) with around 2200 total citations. The average impact factor of his publications is >6 and his current H index is 22 (google scholar).

He has obtained signifiant funding from industry in the last 5 years (>$250,000) for several high-impact research projects (see also Projects).

http://scholar.google.com/citations?user=yDGFbvsAAAAJ&hl=en

https://www.scopus.com/authid/detail.uri?authorId=15836756200

https://orcid.org/0000-0003-1095-2569

http://www.ncbi.nlm.nih.gov/pubmed/?term=gamsjaeger+r+OR+gamsjager+r

Dr Roland Gamsjaeger's lab focuses on

(1) understanding the molecular mechanism governing the DNA damage response. More specifically, the lab studies structure and function of proteins such as single-stranded DNA binding proteins (e.g., the recently discovered hSSB1). This work is leading deeply into the analysis of DNA repair and chromatin structure and organisation and is aiming at redefining some of the major players in the maintenance of genetic information and lays the groundwork for the future development of successful tailored therapeutics for the treatment of various cancers. For these studies a combination of biochemical, molecular biology and cellular approaches in vitro and in vivo is used.

(2) gaining a molecular understanding of how proteins in SARS CoV-2 functioning together for viral replication. The aim of this research is to develop novel anti-viral drugs to combat Covid-19.

(3) collaborations with industry (see also Projects for co-funded work) in the area of protein characterisation by NMR (structure), BLI or SPR (biosensors) and other biophysical methods.

proteins, structural biology, NMR, biophysics, biochemistry, industry collaborations