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Doctor Zein Amro

  • Associate Lecturer - Medical Science (Human Anatomy and Physiology), School of Science

Accepting HDR Candidates

Available HDR projects

Revisiting AQP water channels in cystogenesis: potential novel therapeutic targeting of AQP1 for ADPKD treatment

20212024

Research activity per year

Personal profile

Biography

Dr. Zein Amro holds a PhD in Biomedicine awarded from the University of Adelaide within the field of Neuroscience. The primary focus of his thesis was investigating the roles of human aquaporin water channels in Tauopathies, particularly, Alzheimer’s Disease. Major discoveries from his PhD included the discovery of two novel aquaporin channels in the human brain with potential protective roles in oxidative stress, a common aetiology of Alzheimer’s Disease. Zein's current research at WSU focuses on the role of aquaporin water channels in the kidney as potential pharmacological targets for the treatment of Autosomal Dominant Polycystic Kidney disease. Zein’s other research interests include mental health disorders, and cancer.

Dr. Amro also has international research experience in Scleroderma and lung fibrosis research at McGill University, Montreal. Work here focused on optimising a high-throughput drug screening protocol utilising patient derived primary fibroblasts cultured in a 3D manner.

Research interests

Aquaporin water channel role in pathogenesis, with primary focus on Autosomal Dominant Polycystic Kidney Disease. Other research areas include aquaporin research in neurodegenerative and psychiatric disorders.

Previous positions

McGill University, Montreal, Canada 

Postdoctoral Research Fellow (2024)

Utilized patient derived fibroblast primary cells cultured in 3D for drug discovery. Area of focus was on Scleroderma.

Previous positions

University of Adelaide, Adelaide, Australia

PhD candidate/ Honours supervisor

Investigated the expression and role of aquaporin water channels in neuroglial cells under cellular stress. Primary area of research was on Alzheimer's Disease and tauopathies.

Qualifications

Doctor of Philosophy, University of Adelaide

Research keywords

  • Neuroscience
  • Neurodegeneration
  • Neurophysiology
  • Aquaporins
  • Oxidative stress
  • Alzheimer's Disease

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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