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A Clinical Decision Support Tool for the Management of Diabetes-Related Foot Ulcers (DRFUs) Using a Topical Haemoglobin Spray

  • Jose Luis Lazaro-Martinez
  • , David G. Armstrong
  • , Paul Chadwick
  • , Andrea Gledhill
  • , Sandra Janssen
  • , Matthew Malone
  • Complutense University
  • University of Southern California
  • Birmingham City University
  • Great Western Hospitals NHS Foundation Trust
  • Elkerliek Hospital
  • Mölnlycke Health Care

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Diabetes related foot ulcers (DFUs) are complex and costly to manage, with the prevalence of non-healing wounds steadily increasing across the globe. Non-healing wounds can occur when clinicians fail to undertake an appropriate assessment, fail to recognise the importance of systemic or local complications, or provide the optimal treatment. The aetiological causes behind non-healing wounds are multifactorial; however, the purpose of this article is to focus on the role of oxygen in non-healing wounds and to introduce readers to advances in the delivery of topical oxygen therapy (TOT) via a haemoglobin spray. Importantly, this article incorporates a clinical decision support tool (CDST) to help clinicians identify the most appropriate individuals for whom topical haemoglobin may be most beneficial and the most appropriate time for introducing the intervention to improve wound healing outcomes.

Original languageEnglish
Article numbere70700
JournalInternational Wound Journal
Volume22
Issue number6
DOIs
Publication statusPublished - Jun 2025

Bibliographical note

Publisher Copyright:
© 2025 The Author(s). International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • clinical decision tool
  • diabetic foot ulcers
  • topical haemoglobin spray
  • topical oxygen therapy
  • wound hypoxia

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