Abstract
This paper introduces a new way to define a genome rearrangement distance, using the concept of mean first passage time from probability theory. Crucially, this distance provides a genuine metric on genome space. We develop the theory and introduce a link to a graph-based zeta function. The approach is very general and can be applied to a wide variety of group-theoretic models of genome evolution.
Original language | English |
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Pages (from-to) | 1971-1992 |
Number of pages | 22 |
Journal | Journal of Mathematical Biology |
Volume | 80 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2020 |
Keywords
- mathematical models
- phylogeny
- probability theory