A mean first passage time genome rearrangement distance

Andrew R. Francis, Henry P. Wynn

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

This paper introduces a new way to define a genome rearrangement distance, using the concept of mean first passage time from probability theory. Crucially, this distance provides a genuine metric on genome space. We develop the theory and introduce a link to a graph-based zeta function. The approach is very general and can be applied to a wide variety of group-theoretic models of genome evolution.
Original languageEnglish
Pages (from-to)1971-1992
Number of pages22
JournalJournal of Mathematical Biology
Volume80
Issue number6
DOIs
Publication statusPublished - 2020

Keywords

  • mathematical models
  • phylogeny
  • probability theory

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