A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently elevated urinary albumin excretion: Protocol and statistical considerations

Anne T. Reutens, Karin Jandeleit-Dahm, Merlin Thomas, Agus Salim, Alysha M. De Livera, Leon A. Bach, Peter G. Colman, Timothy M.E. Davis, Elif I. Ekinci, Greg Fulcher, Peter Shane Hamblin, Mark A. Kotowicz, Richard J. MacIsaac, Claire Morbey, David Simmons, Georgia Soldatos, Gary Wittert, Ted Wu, Mark E. Cooper, Jonathan E. Shaw

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Medicine and Dentistry

Pharmacology, Toxicology and Pharmaceutical Science