A potential application for large diameter pellicular supports in the reversed phase study of ultra high molecular mass polystyrenes

R. A. Shalliker; P. E. Kavanagh; I. M. Russell

doi:10.1007/BF02290362

A potential application for large diameter pellicular supports in the reversed phase study of ultra high molecular mass polystyrenes

R. A. Shalliker, P. E. Kavanagh, I. M. Russell

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Ultra high molecular mass (> 7 million dalton) polystyrenes are prone to degradation in size exclusion chromatography. In gradient elution reversed phase HPLC they do not elute visibly on small particle size porous supports. However, large diameter C18 pellicular particles were successfully employed for reversed phase study of ultra high molecular mass (15 million dalton) polystyrenes without polymer degradation during elution. Although retention for the lower molecular mass polystyrenes was lower than on small diameter porous particles, the medium high molecular mass polystyrenes (0.5-1 million dalton) showed similar retention. The addition of small diameter porous particles in small quantities, to the large diameter pellicular particles, increased the amount of retention of the low molecular mass polystyrenes without affecting the higher molecular mass polystyrenes.

Original language	English
Pages (from-to)	307-312
Number of pages	6
Journal	Chromatographia
Volume	40
Issue number	5-6
DOIs	https://doi.org/10.1007/BF02290362
Publication status	Published - Mar 1995
Externally published	Yes

Keywords

Column liquid chromatography
Pellicular
Polystyrene
Reversed phase
Ultra high molecular mass

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10.1007/BF02290362

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title = "A potential application for large diameter pellicular supports in the reversed phase study of ultra high molecular mass polystyrenes",

abstract = "Ultra high molecular mass (> 7 million dalton) polystyrenes are prone to degradation in size exclusion chromatography. In gradient elution reversed phase HPLC they do not elute visibly on small particle size porous supports. However, large diameter C18 pellicular particles were successfully employed for reversed phase study of ultra high molecular mass (15 million dalton) polystyrenes without polymer degradation during elution. Although retention for the lower molecular mass polystyrenes was lower than on small diameter porous particles, the medium high molecular mass polystyrenes (0.5-1 million dalton) showed similar retention. The addition of small diameter porous particles in small quantities, to the large diameter pellicular particles, increased the amount of retention of the low molecular mass polystyrenes without affecting the higher molecular mass polystyrenes.",

keywords = "Column liquid chromatography, Pellicular, Polystyrene, Reversed phase, Ultra high molecular mass",

author = "Shalliker, {R. A.} and Kavanagh, {P. E.} and Russell, {I. M.}",

year = "1995",

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doi = "10.1007/BF02290362",

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journal = "Chromatographia",

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T1 - A potential application for large diameter pellicular supports in the reversed phase study of ultra high molecular mass polystyrenes

AU - Shalliker, R. A.

AU - Kavanagh, P. E.

AU - Russell, I. M.

PY - 1995/3

Y1 - 1995/3

N2 - Ultra high molecular mass (> 7 million dalton) polystyrenes are prone to degradation in size exclusion chromatography. In gradient elution reversed phase HPLC they do not elute visibly on small particle size porous supports. However, large diameter C18 pellicular particles were successfully employed for reversed phase study of ultra high molecular mass (15 million dalton) polystyrenes without polymer degradation during elution. Although retention for the lower molecular mass polystyrenes was lower than on small diameter porous particles, the medium high molecular mass polystyrenes (0.5-1 million dalton) showed similar retention. The addition of small diameter porous particles in small quantities, to the large diameter pellicular particles, increased the amount of retention of the low molecular mass polystyrenes without affecting the higher molecular mass polystyrenes.

AB - Ultra high molecular mass (> 7 million dalton) polystyrenes are prone to degradation in size exclusion chromatography. In gradient elution reversed phase HPLC they do not elute visibly on small particle size porous supports. However, large diameter C18 pellicular particles were successfully employed for reversed phase study of ultra high molecular mass (15 million dalton) polystyrenes without polymer degradation during elution. Although retention for the lower molecular mass polystyrenes was lower than on small diameter porous particles, the medium high molecular mass polystyrenes (0.5-1 million dalton) showed similar retention. The addition of small diameter porous particles in small quantities, to the large diameter pellicular particles, increased the amount of retention of the low molecular mass polystyrenes without affecting the higher molecular mass polystyrenes.

KW - Column liquid chromatography

KW - Pellicular

KW - Polystyrene

KW - Reversed phase

KW - Ultra high molecular mass

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JO - Chromatographia

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IS - 5-6

ER -

A potential application for large diameter pellicular supports in the reversed phase study of ultra high molecular mass polystyrenes

Abstract

Keywords

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