TY - JOUR
T1 - A preliminary investigation of cognitive function in rheumatoid arthritis patients on long-term methotrexate treatment
AU - Meade, Tanya
AU - Cumming, Steven
AU - Hallab, Lisa
AU - Spencer, David
AU - Howe, Graydon
AU - Manolios, Nicholas
PY - 2013
Y1 - 2013
N2 - Some studies suggest that cognitive function is impaired in rheumatoid arthritis patients. One possible influence may be commonly used rheumatoid arthritis treatment, methotrexate. This study examined cognitive function in long-term methotrexate users with rheumatoid arthritis and, using a 24-hour pre- and post-methotrexate dose administration, investigated whether there may be transient cognitive function changes. Rheumatoid arthritis patients (n = 35) were assessed immediately before taking methotrexate and 24 hours later. Low and high methotrexate dose groups were then compared. Cognitive performance was unchanged across two assessment points and was within the normal range, although lower in high methotrexate dose group.
AB - Some studies suggest that cognitive function is impaired in rheumatoid arthritis patients. One possible influence may be commonly used rheumatoid arthritis treatment, methotrexate. This study examined cognitive function in long-term methotrexate users with rheumatoid arthritis and, using a 24-hour pre- and post-methotrexate dose administration, investigated whether there may be transient cognitive function changes. Rheumatoid arthritis patients (n = 35) were assessed immediately before taking methotrexate and 24 hours later. Low and high methotrexate dose groups were then compared. Cognitive performance was unchanged across two assessment points and was within the normal range, although lower in high methotrexate dose group.
UR - http://hdl.handle.net/1959.7/uws:18439
U2 - 10.1177/1359105312461660
DO - 10.1177/1359105312461660
M3 - Article
SN - 1359-1053
VL - 18
SP - 1353
EP - 1359
JO - Journal of Health Psychology
JF - Journal of Health Psychology
IS - 10
ER -