A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy : the PIVOT trail

Annemarie Hennessy; Charlene Thornton; Angela Makris; Robert F. Ogle; David J. Henderson-Smart; Adrian Gillin; Andrew Child

A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy : the PIVOT trail

Annemarie Hennessy, Charlene Thornton, Angela Makris, Robert F. Ogle, David J. Henderson-Smart, Adrian Gillin, Andrew Child

Research output: Contribution to journal › Article

Abstract

Aims: Diazoxide is one of few available agents for treatment of hypertensive emergencies in pregnancy. From previous studies, there is a question concerning safety after moderate-dose administration caused episodes of hypotension. Rapid control of severe hypertension is necessary to reduce maternal morbidity, for example, stroke and placental abruption. This study was designed to compare the efficacy of mini-bolus diazoxide with intravenous (i.v.) hydralazine.

Original language	English
Number of pages	7
Journal	Australian and New Zealand Journal of Obstetrics and Gynecology
Publication status	Published - 2007

Keywords

diazoxide
hydralazine
hypertensive crisis
pre-eclampsia

Cite this

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title = "A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy : the PIVOT trail",

abstract = "Aims: Diazoxide is one of few available agents for treatment of hypertensive emergencies in pregnancy. From previous studies, there is a question concerning safety after moderate-dose administration caused episodes of hypotension. Rapid control of severe hypertension is necessary to reduce maternal morbidity, for example, stroke and placental abruption. This study was designed to compare the efficacy of mini-bolus diazoxide with intravenous (i.v.) hydralazine.",

keywords = "diazoxide, hydralazine, hypertensive crisis, pre-eclampsia",

author = "Annemarie Hennessy and Charlene Thornton and Angela Makris and Ogle, {Robert F.} and Henderson-Smart, {David J.} and Adrian Gillin and Andrew Child",

year = "2007",

language = "English",

journal = "Australian and New Zealand Journal of Obstetrics and Gynecology",

issn = "0004-8666",

publisher = "Blackwell",

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TY - JOUR

T1 - A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy : the PIVOT trail

AU - Hennessy, Annemarie

AU - Thornton, Charlene

AU - Makris, Angela

AU - Ogle, Robert F.

AU - Henderson-Smart, David J.

AU - Gillin, Adrian

AU - Child, Andrew

PY - 2007

Y1 - 2007

N2 - Aims: Diazoxide is one of few available agents for treatment of hypertensive emergencies in pregnancy. From previous studies, there is a question concerning safety after moderate-dose administration caused episodes of hypotension. Rapid control of severe hypertension is necessary to reduce maternal morbidity, for example, stroke and placental abruption. This study was designed to compare the efficacy of mini-bolus diazoxide with intravenous (i.v.) hydralazine.

AB - Aims: Diazoxide is one of few available agents for treatment of hypertensive emergencies in pregnancy. From previous studies, there is a question concerning safety after moderate-dose administration caused episodes of hypotension. Rapid control of severe hypertension is necessary to reduce maternal morbidity, for example, stroke and placental abruption. This study was designed to compare the efficacy of mini-bolus diazoxide with intravenous (i.v.) hydralazine.

KW - diazoxide

KW - hydralazine

KW - hypertensive crisis

KW - pre-eclampsia

UR - http://handle.uws.edu.au:8081/1959.7/34496

M3 - Article

SN - 0004-8666

JO - Australian and New Zealand Journal of Obstetrics and Gynecology

JF - Australian and New Zealand Journal of Obstetrics and Gynecology

ER -

A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy : the PIVOT trail

Abstract

Keywords

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