A representation-theoretic approach to the calculation of evolutionary distance in bacteria

Jeremy G. Sumner, Peter D. Jarvis, Andrew R. Francis

Research output: Contribution to journalArticlepeer-review

Abstract

In the context of bacteria and models of their evolution under genome rearrangement, we explore a novel application of group representation theory to the inference of evolutionary history. Our contribution is to show, in a very general maximum likelihood setting, how to use elementary matrix algebra to sidestep intractable combinatorial computations and convert the problem into one of eigenvalue estimation amenable to standard numerical approximation techniques.
Original languageEnglish
Article number335601
Number of pages14
JournalJournal of Physics A: Mathematical and Theoretical
Volume50
Issue number33
DOIs
Publication statusPublished - 2017

Keywords

  • Genomes
  • Phylogeny
  • bacteria
  • genetic transformation
  • group theory

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