Acronyols A and B, new anti-inflammatory prenylated phloroglucinols from the fruits of Acronychia crassipetala

Ritesh Raju; Shintu Mathew; Ahilya Singh; Paul Reddell; Gerald Münch

doi:10.1080/14786419.2021.1986711

Acronyols A and B, new anti-inflammatory prenylated phloroglucinols from the fruits of Acronychia crassipetala

Ritesh Raju, Shintu Mathew, Ahilya Singh, Paul Reddell, Gerald Münch

Western Sydney University

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Two new phloroglucinols, acronyols A (1) and B (2) along with the four known (3-6) pholoroglucinols were identified following anti-inflammatory activity guided fractionation from the fruits of Acronychia crassipetala (family Rutaceae). The pholoroglucinols (1-6) were evaluated for their inhibitory effects on NO production and downregulation of TNF-Î± in RAW 264.7 macrophage cell lines.

Original language	English
Pages (from-to)	4358-4364
Number of pages	7
Journal	Natural Product Research
Volume	36
Issue number	17
DOIs	https://doi.org/10.1080/14786419.2021.1986711
Publication status	Published - 2022

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© 2021 Informa UK Limited, trading as Taylor & Francis Group.

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title = "Acronyols A and B, new anti-inflammatory prenylated phloroglucinols from the fruits of Acronychia crassipetala",

abstract = "Two new phloroglucinols, acronyols A (1) and B (2) along with the four known (3-6) pholoroglucinols were identified following anti-inflammatory activity guided fractionation from the fruits of Acronychia crassipetala (family Rutaceae). The pholoroglucinols (1-6) were evaluated for their inhibitory effects on NO production and downregulation of TNF-{\^I}± in RAW 264.7 macrophage cell lines.",

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AU - Raju, Ritesh

AU - Mathew, Shintu

AU - Singh, Ahilya

AU - Reddell, Paul

AU - Münch, Gerald

PY - 2022

Y1 - 2022

N2 - Two new phloroglucinols, acronyols A (1) and B (2) along with the four known (3-6) pholoroglucinols were identified following anti-inflammatory activity guided fractionation from the fruits of Acronychia crassipetala (family Rutaceae). The pholoroglucinols (1-6) were evaluated for their inhibitory effects on NO production and downregulation of TNF-Î± in RAW 264.7 macrophage cell lines.

AB - Two new phloroglucinols, acronyols A (1) and B (2) along with the four known (3-6) pholoroglucinols were identified following anti-inflammatory activity guided fractionation from the fruits of Acronychia crassipetala (family Rutaceae). The pholoroglucinols (1-6) were evaluated for their inhibitory effects on NO production and downregulation of TNF-Î± in RAW 264.7 macrophage cell lines.

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DO - 10.1080/14786419.2021.1986711

M3 - Article

SN - 1478-6419

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JO - Natural Product Research

JF - Natural Product Research

IS - 17

ER -

Acronyols A and B, new anti-inflammatory prenylated phloroglucinols from the fruits of Acronychia crassipetala

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