Airflow dynamics and aerosol particle transport in a human lung

![CDATA[The knowledge of the aerosol particle transport and deposition (TD) is essential for the health risk assessment and the targeted drug delivery in a respiratory tract. Many studies have been performed for the airflow characterization at the mouth-throat and oral airways. The precise understanding of the airflow and particle dynamics at the upper lung airways could improve the TD. Therefore, an advanced numerical framework is developed for the particle TD into the human lung airway grounded upon Weibel’s lung model. Primarily this study intends to examine the particle TD based on inhalation condition in the human lung by using the ANSYS Fluent software. Particle deposition efficiency is calculated based on the Euler-Lagrange (E-L) approach. Also, the different particle diameter (1 μm ≤dp≤10μm) factor for deposition is discussed. The preliminary results suggest that the particle deposition efficiency increases with the increase of the Reynolds number and the particle diameter in the lung airways.]]