An enhanced miniaturized assay for antimicrobial prospecting

Shannon M. Smith, Andrew J. Beattie, Michael R. Gillings, Marita P. Holley, Adam J. Stow, Christine L. Turnbull, Peter D. Wilson, David A. Briscoe

    Research output: Contribution to journalArticlepeer-review

    21 Citations (Scopus)

    Abstract

    Bioprospecting for novel antimicrobials increasingly relies on extremely small samples unsuitable for conventional bulk extraction and assay. We developed a microtitre plate assay for minimal amounts of test materials which is rapid, extremely sensitive, allows time-course analysis and reduces false negatives. Developed for the analyses of antimicrobial sensitivity and resistance, the technique is appropriate for assays where source materials are scarce.
    Original languageEnglish
    Pages (from-to)103-106
    Number of pages4
    JournalJournal of Microbiological Methods
    Volume72
    Issue number1
    DOIs
    Publication statusPublished - 2008

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