An enhanced miniaturized assay for antimicrobial prospecting

Shannon M. Smith, Andrew J. Beattie, Michael R. Gillings, Marita P. Holley, Adam J. Stow, Christine L. Turnbull, Peter D. Wilson, David A. Briscoe

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Bioprospecting for novel antimicrobials increasingly relies on extremely small samples unsuitable for conventional bulk extraction and assay. We developed a microtitre plate assay for minimal amounts of test materials which is rapid, extremely sensitive, allows time-course analysis and reduces false negatives. Developed for the analyses of antimicrobial sensitivity and resistance, the technique is appropriate for assays where source materials are scarce.
Original languageEnglish
Pages (from-to)103-106
Number of pages4
JournalJournal of Microbiological Methods
Volume72
Issue number1
DOIs
Publication statusPublished - 2008

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