An enhanced miniaturized assay for antimicrobial prospecting

Shannon M. Smith; Andrew J. Beattie; Michael R. Gillings; Marita P. Holley; Adam J. Stow; Christine L. Turnbull; Peter D. Wilson; David A. Briscoe

doi:10.1016/j.mimet.2007.10.003

An enhanced miniaturized assay for antimicrobial prospecting

Shannon M. Smith
, Andrew J. Beattie
, Michael R. Gillings
, Marita P. Holley
, Adam J. Stow
, Christine L. Turnbull
, Peter D. Wilson
, David A. Briscoe

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Bioprospecting for novel antimicrobials increasingly relies on extremely small samples unsuitable for conventional bulk extraction and assay. We developed a microtitre plate assay for minimal amounts of test materials which is rapid, extremely sensitive, allows time-course analysis and reduces false negatives. Developed for the analyses of antimicrobial sensitivity and resistance, the technique is appropriate for assays where source materials are scarce.

Original language	English
Pages (from-to)	103-106
Number of pages	4
Journal	Journal of Microbiological Methods
Volume	72
Issue number	1
DOIs	https://doi.org/10.1016/j.mimet.2007.10.003
Publication status	Published - 2008

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10.1016/j.mimet.2007.10.003

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title = "An enhanced miniaturized assay for antimicrobial prospecting",

abstract = "Bioprospecting for novel antimicrobials increasingly relies on extremely small samples unsuitable for conventional bulk extraction and assay. We developed a microtitre plate assay for minimal amounts of test materials which is rapid, extremely sensitive, allows time-course analysis and reduces false negatives. Developed for the analyses of antimicrobial sensitivity and resistance, the technique is appropriate for assays where source materials are scarce.",

author = "Smith, \{Shannon M.\} and Beattie, \{Andrew J.\} and Gillings, \{Michael R.\} and Holley, \{Marita P.\} and Stow, \{Adam J.\} and Turnbull, \{Christine L.\} and Wilson, \{Peter D.\} and Briscoe, \{David A.\}",

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AU - Smith, Shannon M.

AU - Beattie, Andrew J.

AU - Gillings, Michael R.

AU - Holley, Marita P.

AU - Stow, Adam J.

AU - Turnbull, Christine L.

AU - Wilson, Peter D.

AU - Briscoe, David A.

PY - 2008

Y1 - 2008

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AB - Bioprospecting for novel antimicrobials increasingly relies on extremely small samples unsuitable for conventional bulk extraction and assay. We developed a microtitre plate assay for minimal amounts of test materials which is rapid, extremely sensitive, allows time-course analysis and reduces false negatives. Developed for the analyses of antimicrobial sensitivity and resistance, the technique is appropriate for assays where source materials are scarce.

UR - http://handle.uws.edu.au:8081/1959.7/546435

U2 - 10.1016/j.mimet.2007.10.003

DO - 10.1016/j.mimet.2007.10.003

M3 - Article

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VL - 72

SP - 103

EP - 106

JO - Journal of Microbiological Methods

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ER -

An enhanced miniaturized assay for antimicrobial prospecting

Abstract

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