Abstract
The previous edition's chapter was a comprehensive and detailed outline of derivatization analytical techniques, that has been updated with a stronger emphasis on recent literature. The two main methods to incorporate a derivatization step in the analytical workflow are: (1) before/pre-column separation or (2) after/post-column separation. Derivatization has several advantages with enhancing the detection selectivity and sensitivity of specific compounds/groups of compounds that are present in your injected sample. This chapter includes a focus on GC, LC, methods, quantitation, specific applications and an additional section focused on recently designed column technologies for HPLC post-column derivatizations.
| Original language | English |
|---|---|
| Title of host publication | Comprehensive Sampling and Sample Preparation |
| Editors | Mustafa Soylak |
| Publisher | Academic Press |
| Chapter | 28 |
| Pages | 649-690 |
| Volume | 2 |
| Edition | 2nd |
| ISBN (Electronic) | 9780443159794 |
| ISBN (Print) | 9780443159787 |
| DOIs | |
| Publication status | Published - 2025 |
Keywords
- Acylation
- Alkylation
- Analytical derivatization techniques
- Derivatization reagents
- ECD
- Esterification
- GC/MS
- HPLC
- Sample handling and conditions
- Silylation
Fingerprint
Dive into the research topics of 'Analytical derivatization techniques'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver