Aneuploid islet cell tumor with late metastasis

C. Soon Lee; Ivo D.A. Vellar; Renee Page; Gordon Ennis; Frank Alford; Jürgen Rode

doi:10.1080/00313029400169781

Aneuploid islet cell tumor with late metastasis

C. Soon Lee
, Ivo D.A. Vellar
, Renee Page
, Gordon Ennis
, Frank Alford
, Jürgen Rode

University of Melbourne

Research output: Contribution to journal › Article › peer-review

Abstract

An unusual case of insulin producing islet cell tumor is reported which recurred after a 16 yr interval. In most instances malignancy of islet cell tumors is impossible to assess morphologically or functionally but depends on the recognition of metastases.Nuclear DNA analysis provides significant prognostic and biological information in a number of solid human tumors.Retrospective computerized nuclear image analysis of the primary tumor in the present case showed an aneuploid DNA profile similar to that seen in the metastasis. It appears that ploidy studies may be useful in predicting malignant potential of islet cell tumors.

Original language	English
Pages (from-to)	333-336
Number of pages	4
Journal	Pathology
Volume	26
Issue number	3
DOIs	https://doi.org/10.1080/00313029400169781
Publication status	Published - 1994
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Insulinoma
Islet cell tumor
Malignant
Ploidy

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10.1080/00313029400169781

Cite this

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title = "Aneuploid islet cell tumor with late metastasis",

abstract = "An unusual case of insulin producing islet cell tumor is reported which recurred after a 16 yr interval. In most instances malignancy of islet cell tumors is impossible to assess morphologically or functionally but depends on the recognition of metastases.Nuclear DNA analysis provides significant prognostic and biological information in a number of solid human tumors.Retrospective computerized nuclear image analysis of the primary tumor in the present case showed an aneuploid DNA profile similar to that seen in the metastasis. It appears that ploidy studies may be useful in predicting malignant potential of islet cell tumors.",

keywords = "Insulinoma, Islet cell tumor, Malignant, Ploidy",

author = "Lee, \{C. Soon\} and Vellar, \{Ivo D.A.\} and Renee Page and Gordon Ennis and Frank Alford and J{\"u}rgen Rode",

year = "1994",

doi = "10.1080/00313029400169781",

language = "English",

volume = "26",

pages = "333--336",

journal = "Pathology",

issn = "0031-3025",

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TY - JOUR

T1 - Aneuploid islet cell tumor with late metastasis

AU - Lee, C. Soon

AU - Vellar, Ivo D.A.

AU - Page, Renee

AU - Ennis, Gordon

AU - Alford, Frank

AU - Rode, Jürgen

PY - 1994

Y1 - 1994

N2 - An unusual case of insulin producing islet cell tumor is reported which recurred after a 16 yr interval. In most instances malignancy of islet cell tumors is impossible to assess morphologically or functionally but depends on the recognition of metastases.Nuclear DNA analysis provides significant prognostic and biological information in a number of solid human tumors.Retrospective computerized nuclear image analysis of the primary tumor in the present case showed an aneuploid DNA profile similar to that seen in the metastasis. It appears that ploidy studies may be useful in predicting malignant potential of islet cell tumors.

AB - An unusual case of insulin producing islet cell tumor is reported which recurred after a 16 yr interval. In most instances malignancy of islet cell tumors is impossible to assess morphologically or functionally but depends on the recognition of metastases.Nuclear DNA analysis provides significant prognostic and biological information in a number of solid human tumors.Retrospective computerized nuclear image analysis of the primary tumor in the present case showed an aneuploid DNA profile similar to that seen in the metastasis. It appears that ploidy studies may be useful in predicting malignant potential of islet cell tumors.

KW - Insulinoma

KW - Islet cell tumor

KW - Malignant

KW - Ploidy

UR - https://www.scopus.com/pages/publications/0028477229

U2 - 10.1080/00313029400169781

DO - 10.1080/00313029400169781

M3 - Article

C2 - 7991294

AN - SCOPUS:0028477229

SN - 0031-3025

VL - 26

SP - 333

EP - 336

JO - Pathology

JF - Pathology

IS - 3

ER -

Aneuploid islet cell tumor with late metastasis

Abstract

UN SDGs

Keywords

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