TY - JOUR
T1 - Angiolactone, a new Butyrolactone isolated from the terrestrial myxobacterium, Angiococcus sp.
AU - Raju, Ritesh
AU - Garcia, Ronald
AU - Müller, Rolf
PY - 2014
Y1 - 2014
N2 - Myxobacteria are recognized as one of the outstanding prokaryotic sources of bioactive compounds in nature. More than 100 core structures with diverse biological activities had been elucidated, most of which were novel. In the continuous screening program for anti-infectives focusing on novel, rare, and unexplored myxobacterial taxa, great potential was discovered in Angiococcus disciformis SBAn001. The strain was routinely cultivated in TS-6 medium (Tryptone (Difco) 0.6%, MgSO4 - 7H2O 0.2%, soluble starch (Roth) 0.4%, HEPES 1.19%, pH adjusted to 7.2 with KOH before autoclaving).
AB - Myxobacteria are recognized as one of the outstanding prokaryotic sources of bioactive compounds in nature. More than 100 core structures with diverse biological activities had been elucidated, most of which were novel. In the continuous screening program for anti-infectives focusing on novel, rare, and unexplored myxobacterial taxa, great potential was discovered in Angiococcus disciformis SBAn001. The strain was routinely cultivated in TS-6 medium (Tryptone (Difco) 0.6%, MgSO4 - 7H2O 0.2%, soluble starch (Roth) 0.4%, HEPES 1.19%, pH adjusted to 7.2 with KOH before autoclaving).
UR - http://handle.uws.edu.au:8081/1959.7/552193
U2 - 10.1038/ja.2014.55
DO - 10.1038/ja.2014.55
M3 - Article
SN - 0021-8820
VL - 67
SP - 725
EP - 726
JO - Journal of Antibiotics
JF - Journal of Antibiotics
ER -