Anti-inflammatory activity of prenyl and geranyloxy furanocoumarins from Citrus garrawayi (Rutaceae)

Ritesh Raju; Ahilya Singh; Paul Reddell; Gerald Münch

doi:10.1016/j.phytol.2018.07.030

Anti-inflammatory activity of prenyl and geranyloxy furanocoumarins from Citrus garrawayi (Rutaceae)

Ritesh Raju, Ahilya Singh, Paul Reddell, Gerald Münch

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Anti-inflammatory activity guided isolation from Citrus garrawayi (Rutaceae) led to the discovery of five new garracoumarins A" E (1 - 5), and five known (6" 10) isoprenylated furanocoumarins and the known sterol bourjotinolone A (11). Discussed herein is the anti-inflammatory structure activity relationship of the ten furanocoumarins and a detailed spectroscopic analysis leading to the structure elucidation of the new and known isoprenylated furanocoumarins.

Original language	English
Pages (from-to)	197-202
Number of pages	6
Journal	Phytochemistry Letters
Volume	27
DOIs	https://doi.org/10.1016/j.phytol.2018.07.030
Publication status	Published - Oct 2018

Bibliographical note

Publisher Copyright:
© 2018 Phytochemical Society of Europe

Keywords

Rutaceae
anti-inflammatory agents
citrus
isoprene
plant products

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10.1016/j.phytol.2018.07.030

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title = "Anti-inflammatory activity of prenyl and geranyloxy furanocoumarins from Citrus garrawayi (Rutaceae)",

abstract = "Anti-inflammatory activity guided isolation from Citrus garrawayi (Rutaceae) led to the discovery of five new garracoumarins A{"} E (1 - 5), and five known (6{"} 10) isoprenylated furanocoumarins and the known sterol bourjotinolone A (11). Discussed herein is the anti-inflammatory structure activity relationship of the ten furanocoumarins and a detailed spectroscopic analysis leading to the structure elucidation of the new and known isoprenylated furanocoumarins.",

keywords = "Rutaceae, anti-inflammatory agents, citrus, isoprene, plant products",

author = "Ritesh Raju and Ahilya Singh and Paul Reddell and Gerald M{\"u}nch",

note = "Publisher Copyright: {\textcopyright} 2018 Phytochemical Society of Europe",

year = "2018",

month = oct,

doi = "10.1016/j.phytol.2018.07.030",

language = "English",

volume = "27",

pages = "197--202",

journal = "Phytochemistry Letters",

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T1 - Anti-inflammatory activity of prenyl and geranyloxy furanocoumarins from Citrus garrawayi (Rutaceae)

AU - Raju, Ritesh

AU - Singh, Ahilya

AU - Reddell, Paul

AU - Münch, Gerald

PY - 2018/10

Y1 - 2018/10

N2 - Anti-inflammatory activity guided isolation from Citrus garrawayi (Rutaceae) led to the discovery of five new garracoumarins A" E (1 - 5), and five known (6" 10) isoprenylated furanocoumarins and the known sterol bourjotinolone A (11). Discussed herein is the anti-inflammatory structure activity relationship of the ten furanocoumarins and a detailed spectroscopic analysis leading to the structure elucidation of the new and known isoprenylated furanocoumarins.

AB - Anti-inflammatory activity guided isolation from Citrus garrawayi (Rutaceae) led to the discovery of five new garracoumarins A" E (1 - 5), and five known (6" 10) isoprenylated furanocoumarins and the known sterol bourjotinolone A (11). Discussed herein is the anti-inflammatory structure activity relationship of the ten furanocoumarins and a detailed spectroscopic analysis leading to the structure elucidation of the new and known isoprenylated furanocoumarins.

KW - Rutaceae

KW - anti-inflammatory agents

KW - citrus

KW - isoprene

KW - plant products

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:47572

U2 - 10.1016/j.phytol.2018.07.030

DO - 10.1016/j.phytol.2018.07.030

M3 - Article

SN - 1874-3900

VL - 27

SP - 197

EP - 202

JO - Phytochemistry Letters

JF - Phytochemistry Letters

ER -

Anti-inflammatory activity of prenyl and geranyloxy furanocoumarins from Citrus garrawayi (Rutaceae)

Abstract

Bibliographical note

Keywords

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