Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line

Mojtaba Haghighat; Afsoon Naroie; Alireza Rezvani; Mohammad Hakimi; Hamideh Saravani; Majid Darroudi; Abbas Amini; Mohamad Sabaghan; Mehrdad Khatami

doi:10.1007/s12668-021-00887-6

Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line

Mojtaba Haghighat, Afsoon Naroie, Alireza Rezvani, Mohammad Hakimi, Hamideh Saravani, Majid Darroudi, Abbas Amini, Mohamad Sabaghan, Mehrdad Khatami

Western Sydney University

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A novel lanthanum (III) complex with 8-Hq = 8-hydroxy quinoline and phen-dione = 1,10-phenanthroline-5,6-dione was synthesized using the reflux method. The complex was characterized using elemental analyses, cyclic voltammetry technique, electronic absorption spectroscopy, H-NMR spectroscopy, X-ray powder diffraction, and scanning electron microscopy. Then, La2O2(SO4) nanostructure (NS La-s) was obtained from the lanthanum (III) complex as a precursor after calcination at 700Â Â°C for 4Â h. The thermal stability of nanostructure was determined by the thermal gravimetric method. SEM results showed that the morphology of La2O2(SO4) was spiral-like. The cytotoxicity of La-s NS was studied using cell viability assay on neuroblastoma-N2a cell line culture. The results ranked the cytotoxicity activity of La-s NS in N2a cell line to IC50 = ~ 22Â μgÂ mL−1.

Original language	English
Pages (from-to)	696-702
Number of pages	7
Journal	BioNanoScience
Volume	11
Issue number	3
DOIs	https://doi.org/10.1007/s12668-021-00887-6
Publication status	Published - 2021

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title = "Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line",

abstract = "A novel lanthanum (III) complex with 8-Hq = 8-hydroxy quinoline and phen-dione = 1,10-phenanthroline-5,6-dione was synthesized using the reflux method. The complex was characterized using elemental analyses, cyclic voltammetry technique, electronic absorption spectroscopy, H-NMR spectroscopy, X-ray powder diffraction, and scanning electron microscopy. Then, La2O2(SO4) nanostructure (NS La-s) was obtained from the lanthanum (III) complex as a precursor after calcination at 700{\^A} {\^A}°C for 4{\^A} h. The thermal stability of nanostructure was determined by the thermal gravimetric method. SEM results showed that the morphology of La2O2(SO4) was spiral-like. The cytotoxicity of La-s NS was studied using cell viability assay on neuroblastoma-N2a cell line culture. The results ranked the cytotoxicity activity of La-s NS in N2a cell line to IC50 = ~ 22{\^A} μg{\^A} mL−1.",

author = "Mojtaba Haghighat and Afsoon Naroie and Alireza Rezvani and Mohammad Hakimi and Hamideh Saravani and Majid Darroudi and Abbas Amini and Mohamad Sabaghan and Mehrdad Khatami",

year = "2021",

doi = "10.1007/s12668-021-00887-6",

language = "English",

volume = "11",

pages = "696--702",

journal = "BioNanoScience",

issn = "2191-1630",

publisher = "Springer New York",

number = "3",

}

TY - JOUR

T1 - Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line

AU - Haghighat, Mojtaba

AU - Naroie, Afsoon

AU - Rezvani, Alireza

AU - Hakimi, Mohammad

AU - Saravani, Hamideh

AU - Darroudi, Majid

AU - Amini, Abbas

AU - Sabaghan, Mohamad

AU - Khatami, Mehrdad

PY - 2021

Y1 - 2021

N2 - A novel lanthanum (III) complex with 8-Hq = 8-hydroxy quinoline and phen-dione = 1,10-phenanthroline-5,6-dione was synthesized using the reflux method. The complex was characterized using elemental analyses, cyclic voltammetry technique, electronic absorption spectroscopy, H-NMR spectroscopy, X-ray powder diffraction, and scanning electron microscopy. Then, La2O2(SO4) nanostructure (NS La-s) was obtained from the lanthanum (III) complex as a precursor after calcination at 700Â Â°C for 4Â h. The thermal stability of nanostructure was determined by the thermal gravimetric method. SEM results showed that the morphology of La2O2(SO4) was spiral-like. The cytotoxicity of La-s NS was studied using cell viability assay on neuroblastoma-N2a cell line culture. The results ranked the cytotoxicity activity of La-s NS in N2a cell line to IC50 = ~ 22Â μgÂ mL−1.

AB - A novel lanthanum (III) complex with 8-Hq = 8-hydroxy quinoline and phen-dione = 1,10-phenanthroline-5,6-dione was synthesized using the reflux method. The complex was characterized using elemental analyses, cyclic voltammetry technique, electronic absorption spectroscopy, H-NMR spectroscopy, X-ray powder diffraction, and scanning electron microscopy. Then, La2O2(SO4) nanostructure (NS La-s) was obtained from the lanthanum (III) complex as a precursor after calcination at 700Â Â°C for 4Â h. The thermal stability of nanostructure was determined by the thermal gravimetric method. SEM results showed that the morphology of La2O2(SO4) was spiral-like. The cytotoxicity of La-s NS was studied using cell viability assay on neuroblastoma-N2a cell line culture. The results ranked the cytotoxicity activity of La-s NS in N2a cell line to IC50 = ~ 22Â μgÂ mL−1.

UR - https://hdl.handle.net/1959.7/uws:71882

U2 - 10.1007/s12668-021-00887-6

DO - 10.1007/s12668-021-00887-6

M3 - Article

SN - 2191-1630

VL - 11

SP - 696

EP - 702

JO - BioNanoScience

JF - BioNanoScience

IS - 3

ER -

Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line

Abstract

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