Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line

Mojtaba Haghighat; Afsoon Naroie; Alireza Rezvani; Mohammad Hakimi; Hamideh Saravani; Majid Darroudi; Abbas Amini; Mohamad Sabaghan; Mehrdad Khatami

doi:10.1007/s12668-021-00887-6

Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line

Mojtaba Haghighat
, Afsoon Naroie
, Alireza Rezvani
, Mohammad Hakimi
, Hamideh Saravani
, Majid Darroudi
, Abbas Amini
, Mohamad Sabaghan
, Mehrdad Khatami

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A novel lanthanum (III) complex with 8-Hq = 8-hydroxy quinoline and phen-dione = 1,10-phenanthroline-5,6-dione was synthesized using the reflux method. The complex was characterized using elemental analyses, cyclic voltammetry technique, electronic absorption spectroscopy, H-NMR spectroscopy, X-ray powder diffraction, and scanning electron microscopy. Then, La₂O₂(SO₄) nanostructure (NS La-s) was obtained from the lanthanum (III) complex as a precursor after calcination at 700 °C for 4 h. The thermal stability of nanostructure was determined by the thermal gravimetric method. SEM results showed that the morphology of La₂O₂(SO₄) was spiral-like. The cytotoxicity of La-s NS was studied using cell viability assay on neuroblastoma-N2a cell line culture. The results ranked the cytotoxicity activity of La-s NS in N2a cell line to IC₅₀ = ~ 22 μg mL^− 1.

Original language	English
Pages (from-to)	696-702
Number of pages	7
Journal	BioNanoScience
Volume	11
Issue number	3
DOIs	https://doi.org/10.1007/s12668-021-00887-6
Publication status	Published - Sept 2021

Bibliographical note

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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SDG 3 Good Health and Well-being

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10.1007/s12668-021-00887-6

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title = "Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line",

abstract = "A novel lanthanum (III) complex with 8-Hq = 8-hydroxy quinoline and phen-dione = 1,10-phenanthroline-5,6-dione was synthesized using the reflux method. The complex was characterized using elemental analyses, cyclic voltammetry technique, electronic absorption spectroscopy, H-NMR spectroscopy, X-ray powder diffraction, and scanning electron microscopy. Then, La2O2(SO4) nanostructure (NS La-s) was obtained from the lanthanum (III) complex as a precursor after calcination at 700 °C for 4 h. The thermal stability of nanostructure was determined by the thermal gravimetric method. SEM results showed that the morphology of La2O2(SO4) was spiral-like. The cytotoxicity of La-s NS was studied using cell viability assay on neuroblastoma-N2a cell line culture. The results ranked the cytotoxicity activity of La-s NS in N2a cell line to IC50 = \textasciitilde{} 22 μg mL− 1.",

author = "Mojtaba Haghighat and Afsoon Naroie and Alireza Rezvani and Mohammad Hakimi and Hamideh Saravani and Majid Darroudi and Abbas Amini and Mohamad Sabaghan and Mehrdad Khatami",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

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doi = "10.1007/s12668-021-00887-6",

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T1 - Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line

AU - Haghighat, Mojtaba

AU - Naroie, Afsoon

AU - Rezvani, Alireza

AU - Hakimi, Mohammad

AU - Saravani, Hamideh

AU - Darroudi, Majid

AU - Amini, Abbas

AU - Sabaghan, Mohamad

AU - Khatami, Mehrdad

PY - 2021/9

Y1 - 2021/9

N2 - A novel lanthanum (III) complex with 8-Hq = 8-hydroxy quinoline and phen-dione = 1,10-phenanthroline-5,6-dione was synthesized using the reflux method. The complex was characterized using elemental analyses, cyclic voltammetry technique, electronic absorption spectroscopy, H-NMR spectroscopy, X-ray powder diffraction, and scanning electron microscopy. Then, La2O2(SO4) nanostructure (NS La-s) was obtained from the lanthanum (III) complex as a precursor after calcination at 700 °C for 4 h. The thermal stability of nanostructure was determined by the thermal gravimetric method. SEM results showed that the morphology of La2O2(SO4) was spiral-like. The cytotoxicity of La-s NS was studied using cell viability assay on neuroblastoma-N2a cell line culture. The results ranked the cytotoxicity activity of La-s NS in N2a cell line to IC50 = ~ 22 μg mL− 1.

AB - A novel lanthanum (III) complex with 8-Hq = 8-hydroxy quinoline and phen-dione = 1,10-phenanthroline-5,6-dione was synthesized using the reflux method. The complex was characterized using elemental analyses, cyclic voltammetry technique, electronic absorption spectroscopy, H-NMR spectroscopy, X-ray powder diffraction, and scanning electron microscopy. Then, La2O2(SO4) nanostructure (NS La-s) was obtained from the lanthanum (III) complex as a precursor after calcination at 700 °C for 4 h. The thermal stability of nanostructure was determined by the thermal gravimetric method. SEM results showed that the morphology of La2O2(SO4) was spiral-like. The cytotoxicity of La-s NS was studied using cell viability assay on neuroblastoma-N2a cell line culture. The results ranked the cytotoxicity activity of La-s NS in N2a cell line to IC50 = ~ 22 μg mL− 1.

UR - https://hdl.handle.net/1959.7/uws:71882

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DO - 10.1007/s12668-021-00887-6

M3 - Article

SN - 2191-1630

VL - 11

SP - 696

EP - 702

JO - BioNanoScience

JF - BioNanoScience

IS - 3

ER -

Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line

Abstract

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