Applications of fluorescence spectroscopy and confocal microscopy

Anya Salih, Paul Wormell, K. Benjamin Garbutcheon-Singh, Benjamin Harper, Simon Myers, David Geny, Christopher Hammang, Janice Aldrich-Wright

Research output: Chapter in Book / Conference PaperChapter

Abstract

In this chapter we describe the use of fluorescence spectroscopy and confocal microscopy to investigate the DNA binding capacity, uptake route and intracellular localisation of novel metallointercalators. Fluorescence is the property whereby some atoms or molecules absorb UV or visible light and then re-emit it at longer wavelengths after a brief interval, termed the fluorescence lifetime.
Original languageEnglish
Title of host publicationMetallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules
EditorsJanice R. Aldrich-Wright
Place of PublicationU.S.
PublisherSpringer
Pages235-272
Number of pages38
ISBN (Electronic)9783211990797
ISBN (Print)9783211094273
DOIs
Publication statusPublished - 2011

Fingerprint

Dive into the research topics of 'Applications of fluorescence spectroscopy and confocal microscopy'. Together they form a unique fingerprint.

Cite this