Association between antioxidant intake/status and obesity : a systematic review of observational studies

Banafshe Hosseini, Ahmad Saedisomeolia, Margaret Allman-Farinelli

Research output: Contribution to journalArticlepeer-review

Abstract

The global prevalence of obesity has doubled in recent decades. Compelling evidences indicated that obesity was associated with lower concentrations of specific antioxidants which may play a role in the development of obesity-related diseases such as cardiovascular disease. The present review aimed to synthesize the evidence from studies on the association between obesity and antioxidant micronutrients in a systematic manner. Data bases including MEDLINE, Science Direct, and Cochrane were searched from inception to October 2015. Thirty-one articles were reviewed using the MOOSE checklist. Lower concentrations of antioxidants have been reported in obese individuals among age groups worldwide. Circulatory levels of carotenoids, vitamins E and C, as well as zinc, magnesium, and selenium were inversely correlated with obesity and body fat mass. However, studies demonstrated inconsistencies in findings. Lower status of carotenoids, vitamins E and C, zinc, magnesium, and selenium appears to be associated with adiposity. Intervention studies may be needed to establish the causality of these associations.
Original languageEnglish
Pages (from-to)287-297
Number of pages11
JournalBiological Trace Element Research
Volume175
Issue number2
DOIs
Publication statusPublished - 2017

Keywords

  • carotenoids
  • obesity
  • vitamin C
  • vitamin E
  • zinc

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