TY - JOUR
T1 - Association between urinary incontinence and frailty : a systematic review and meta-analysis
AU - Veronese, Nicola
AU - Soysal, Pinar
AU - Stubbs, Brendon
AU - Marengoni, Alessandra
AU - Demurtas, Jacopo
AU - Maggi, Stefania
AU - Petrovic, Mirko
AU - Verdejo‑Bravo, Carlos
AU - Aharony, L.
AU - De Cock, J.
AU - Nuotio, M. S.
AU - Pedone, C.
AU - Rifel, J.
AU - Vande Walle, N.
AU - Velghe, A.
AU - Vella, A.
AU - Solmi, M.
AU - Koyanagi, A.
AU - Thompson, T.
AU - Beudart, C.
AU - Bruyère, O.
AU - Torbahn, G.
AU - Firth, J.
AU - Smith, L.
PY - 2018
Y1 - 2018
N2 - Purpose: Urinary incontinence (UI) and frailty are common geriatric syndromes. Although literature increasingly supports a relationship between these two conditions, no systematic review and meta-analysis has been performed on this topic. Therefore, we aimed to investigate the potential association between UI and frailty, through a meta-analytic approach. Methods: A systematic search in major databases was undertaken until 15th March 2018 for studies reporting the association between UI and frailty. The prevalence of UI in people with frailty (vs. those without) was pooled through an odds ratio (OR) and 95% confidence intervals (CIs), with a random-effects model. The other outcomes were summarized descriptively. Results: Among 828 papers, 11 articles were eligible, including 3784 participants (mean age 78.2 years; 55.1% women). The prevalence of UI was 39.1% in people with frailty and 19.4% in those without. A meta-analysis with five studies (1540 participants) demonstrated that UI was over twice as likely in frail people versus those without (OR 2.28; 95% CI 1.35–3.86; I2 = 61%). One cross-sectional study, adjusting for potential confounders and one longitudinal study confirmed that UI is significantly associated with frailty. In two cross-sectional studies, using adjusted analyses, frailty was more common in people with UI. Conclusion: Urinary incontinence is twice as common in older people with frailty compared to older people without frailty. Screening and the development of interventions for UI and frailty could prove useful for this common comorbidity.
AB - Purpose: Urinary incontinence (UI) and frailty are common geriatric syndromes. Although literature increasingly supports a relationship between these two conditions, no systematic review and meta-analysis has been performed on this topic. Therefore, we aimed to investigate the potential association between UI and frailty, through a meta-analytic approach. Methods: A systematic search in major databases was undertaken until 15th March 2018 for studies reporting the association between UI and frailty. The prevalence of UI in people with frailty (vs. those without) was pooled through an odds ratio (OR) and 95% confidence intervals (CIs), with a random-effects model. The other outcomes were summarized descriptively. Results: Among 828 papers, 11 articles were eligible, including 3784 participants (mean age 78.2 years; 55.1% women). The prevalence of UI was 39.1% in people with frailty and 19.4% in those without. A meta-analysis with five studies (1540 participants) demonstrated that UI was over twice as likely in frail people versus those without (OR 2.28; 95% CI 1.35–3.86; I2 = 61%). One cross-sectional study, adjusting for potential confounders and one longitudinal study confirmed that UI is significantly associated with frailty. In two cross-sectional studies, using adjusted analyses, frailty was more common in people with UI. Conclusion: Urinary incontinence is twice as common in older people with frailty compared to older people without frailty. Screening and the development of interventions for UI and frailty could prove useful for this common comorbidity.
KW - frail elderly
KW - urinary incontinence
UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:48161
U2 - 10.1007/s41999-018-0102-y
DO - 10.1007/s41999-018-0102-y
M3 - Article
SN - 1878-7649
VL - 9
SP - 571
EP - 578
JO - European Geriatric Medicine
JF - European Geriatric Medicine
IS - 5
ER -