Biomarkers in metastatic colorectal cancer: Predicting prognosis and therapeutic response

Connie I. Diakos; Kellie A. Charles; Wei Chua; Viive M. Howell; Stephen J. Clarke

doi:10.1007/978-94-007-7681-4_1

Biomarkers in metastatic colorectal cancer: Predicting prognosis and therapeutic response

Connie I. Diakos, Kellie A. Charles, Wei Chua, Viive M. Howell, Stephen J. Clarke

Research output: Chapter in Book / Conference Paper › Chapter › peer-review

Abstract

Significant advances in chemotherapeutics over the past decade have seen a doubling in the median survival time of patients with metastatic colorectal cancer. However, this comes at the cost of toxicity to the patient and financial burden to the community. Biomarkers to predict disease course and treatment response are therefore of major importance so as to allow for the judicious selection of treatment candidates and agents and doses. This review seeks to summarize the current markers available for the prediction of prognosis and treatment response in metastatic colorectal cancer.

Original language	English
Title of host publication	Biomarkers in Disease
Subtitle of host publication	Methods, Discoveries and Applications: Biomarkers in Cancer
Publisher	Springer Netherlands
Pages	601-629
Number of pages	29
ISBN (Electronic)	9789400776814
ISBN (Print)	9789400776807
DOIs	https://doi.org/10.1007/978-94-007-7681-4_1
Publication status	Published - 1 Jan 2015
Externally published	Yes

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media Dordrecht 2015.

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10.1007/978-94-007-7681-4_1

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AU - Clarke, Stephen J.

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Biomarkers in metastatic colorectal cancer: Predicting prognosis and therapeutic response

Abstract

Bibliographical note

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