BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant : a case report

Lucy McMullen; Liane Khoo; Lyndal Anderson; Simone Strasser; David M. Gracey

doi:10.1186/s12879-023-08601-5

BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant : a case report

Lucy McMullen, Liane Khoo, Lyndal Anderson, Simone Strasser, David M. Gracey

Western Sydney University

Research output: Contribution to journal › Article › peer-review

Abstract

Background: While anaemia following liver transplant is common, anaemia in the context of BK viraemia is not a commonly recognised phenomenon. Case presentation: We present the case of 59-year old gentleman with severe anaemia in the context of BK viraemia and nephropathy following ABO incompatible liver transplant. Severity of anaemia appeared to correlate with high titres of BK virus in the serum. Bone marrow biopsy revealed hypocellular marrow with normal cytogenetics. Anaemia improved with treatment with cidofovir, intravenous immunoglobulin, reduction in immunosuppression and erythropoietin stimulating agent. Conclusion: To our knowledge, this is the first case of anaemia post liver transplant contributed to by BK viraemia.

Original language	English
Article number	609
Number of pages	5
Journal	BMC Infectious Diseases
Volume	23
Issue number	1
DOIs	https://doi.org/10.1186/s12879-023-08601-5
Publication status	Published - Dec 2023

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title = "BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant : a case report",

abstract = "Background: While anaemia following liver transplant is common, anaemia in the context of BK viraemia is not a commonly recognised phenomenon. Case presentation: We present the case of 59-year old gentleman with severe anaemia in the context of BK viraemia and nephropathy following ABO incompatible liver transplant. Severity of anaemia appeared to correlate with high titres of BK virus in the serum. Bone marrow biopsy revealed hypocellular marrow with normal cytogenetics. Anaemia improved with treatment with cidofovir, intravenous immunoglobulin, reduction in immunosuppression and erythropoietin stimulating agent. Conclusion: To our knowledge, this is the first case of anaemia post liver transplant contributed to by BK viraemia.",

author = "Lucy McMullen and Liane Khoo and Lyndal Anderson and Simone Strasser and Gracey, {David M.}",

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T1 - BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant : a case report

AU - McMullen, Lucy

AU - Khoo, Liane

AU - Anderson, Lyndal

AU - Strasser, Simone

AU - Gracey, David M.

PY - 2023/12

Y1 - 2023/12

N2 - Background: While anaemia following liver transplant is common, anaemia in the context of BK viraemia is not a commonly recognised phenomenon. Case presentation: We present the case of 59-year old gentleman with severe anaemia in the context of BK viraemia and nephropathy following ABO incompatible liver transplant. Severity of anaemia appeared to correlate with high titres of BK virus in the serum. Bone marrow biopsy revealed hypocellular marrow with normal cytogenetics. Anaemia improved with treatment with cidofovir, intravenous immunoglobulin, reduction in immunosuppression and erythropoietin stimulating agent. Conclusion: To our knowledge, this is the first case of anaemia post liver transplant contributed to by BK viraemia.

AB - Background: While anaemia following liver transplant is common, anaemia in the context of BK viraemia is not a commonly recognised phenomenon. Case presentation: We present the case of 59-year old gentleman with severe anaemia in the context of BK viraemia and nephropathy following ABO incompatible liver transplant. Severity of anaemia appeared to correlate with high titres of BK virus in the serum. Bone marrow biopsy revealed hypocellular marrow with normal cytogenetics. Anaemia improved with treatment with cidofovir, intravenous immunoglobulin, reduction in immunosuppression and erythropoietin stimulating agent. Conclusion: To our knowledge, this is the first case of anaemia post liver transplant contributed to by BK viraemia.

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DO - 10.1186/s12879-023-08601-5

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VL - 23

JO - BMC Infectious Diseases

JF - BMC Infectious Diseases

IS - 1

M1 - 609

ER -

BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant : a case report

Abstract

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