Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015 : findings from the Global Burden of Disease 2015 Study

x Gbd 2015 Eastern Mediterranean Region Diarrhea Collaborators; Ibrahim Khalil; Charbel El Bcheraoui; Raghid Charara; Maziar Moradi-Lakeh; Ashkan Afshin; Nicholas J. Kassebaum; Michael Collison; Adrienne Chew; Kristopher J. Krohn; Farah Daoud; Danny Colombara; Kyle J. Foreman; William W. Godwin; Michael Kutz; Mojde Mirarefin; Puja C. Rao; Robert Reiner; Christopher Troeger; Haidong Wang; Haftom Niguse Abraha; Remon Abu-Elyazeed; Laith J. Abu-Raddad; Aliasghar Ahmad Kiadaliri; Alireza Ahmadi; Muktar Beshir Ahmed; Khurshid Alam; Reza Alizadeh-Navaei; Rajaa Al-Raddadi; Khalid A. Altirkawi; Nelson Alvis-Guzman; Nahla Anber; Palwasha Anwari; Tesfay Mehari Atey; Euripide Frinel G. Arthur Avokpaho; Umar Bacha; Shahrzad Bazargan-Hejazi; Neeraj Bedi; Isabela M. Bensenor; Adugnaw Berhane; Pascal Obong Bessong; Addisu Shunu Beyene; Zulfiqar A. Bhutta; Geoffrey Colin Buckle; Zahid A. Butt; Hadi Danawi; Amare Deribew; Shirin Djalalinia; Manisha Dubey; Aman Yesuf Endries; Babak Eshrati; Seyed-Mohammad Fereshtehnejad; Florian Fischer; Tsegaye Tewelde Gebrehiwot; Harish Chander Gugnani; Randah Ribhi Hamadeh; Samer Hamidi; Abdullatif Husseini; Spencer Lewis James; Jost B. Jonas; Yousef Saleh Khader; Ejaz Ahmad Khan; Gulfaraz Khan; Jagdish Khubchandani; Niranjan Kissoon; Jacek A. Kopec; Ai Koyanagi; Barthelemy Kuate Defo; Heidi J. Larson; Asma Abdul Latif; Raimundas Lunevicius; Hassan Magdy Abd El Razek; Mohammed Magdy Abd El Razek; Reza Majdzadeh; Azeem Majeed; Reza Malekzadeh; Peter Memiah; Ziad A. Memish; Walter Mendoza; Desalegn Tadese Mengistu; Shafiu Mohammed; Srinivas Murthy; Josephine Wanjiku Ngunjiri; Felix Akpojene Ogbo; Farshad Pourmalek; Amir Radfar; Anwar Rafay; Vafa Rahimi-Movaghar; Rajesh Kumar Rai; Usha Ram; David Laith Rawaf; Salman Rawaf Salman; Andre M. N. Renzaho; Satar Rezaei; Gholamreza Roshandel; Mahdi Safdarian; Mohammad Ali Sahraian; Payman Salamati; Abdallah M. Samy; Juan Ramon Sanabria; Benn Sartorius; Sadaf G. Sepanlou; Masood Ali Shaikh; Mika Shigematsu; Badr H. A. Sobaih; Chandrashekhar T. Sreeramareddy; Bryan L. Sykes; Arash Tehrani-Banihashemi; Mohamad-Hani Temsah; Abdullah Sulieman Terkawi; Tenaw Yimer Tiruye; Roman Topor-Madry; Kingsley Nnanna Ukwaja; Stein Emil Vollset; Tolassa Wakayo; Andrea Werdecker; Charles Shey Wiysonge; Abdulhalik Workicho; Mohsen Yaghoubi; Mehdi Yaseri; Muluken Yenesew; Naohiro Yonemoto; Mustafa Z. Younis; Maysaa El Sayed Zaki; Bassel Zein; Sanjay Zodpey; Aisha O. Jumaan; Theo Vos; Simon I. Hay; Mohsen Naghavi; Christopher J. L. Murray; Ali H. Mokdad

doi:10.1007/s00038-017-1008-z

Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015 : findings from the Global Burden of Disease 2015 Study

x Gbd 2015 Eastern Mediterranean Region Diarrhea Collaborators, Ibrahim Khalil, Charbel El Bcheraoui, Raghid Charara, Maziar Moradi-Lakeh, Ashkan Afshin, Nicholas J. Kassebaum, Michael Collison, Adrienne Chew, Kristopher J. Krohn, Farah Daoud, Danny Colombara, Kyle J. Foreman, William W. Godwin, Michael Kutz, Mojde Mirarefin, Puja C. Rao, Robert Reiner, Christopher Troeger, Haidong WangHaftom Niguse Abraha, Remon Abu-Elyazeed, Laith J. Abu-Raddad, Aliasghar Ahmad Kiadaliri, Alireza Ahmadi, Muktar Beshir Ahmed, Khurshid Alam, Reza Alizadeh-Navaei, Rajaa Al-Raddadi, Khalid A. Altirkawi, Nelson Alvis-Guzman, Nahla Anber, Palwasha Anwari, Tesfay Mehari Atey, Euripide Frinel G. Arthur Avokpaho, Umar Bacha, Shahrzad Bazargan-Hejazi, Neeraj Bedi, Isabela M. Bensenor, Adugnaw Berhane, Pascal Obong Bessong, Addisu Shunu Beyene, Zulfiqar A. Bhutta, Geoffrey Colin Buckle, Zahid A. Butt, Hadi Danawi, Amare Deribew, Shirin Djalalinia, Manisha Dubey, Aman Yesuf Endries, Babak Eshrati, Seyed-Mohammad Fereshtehnejad, Florian Fischer, Tsegaye Tewelde Gebrehiwot, Harish Chander Gugnani, Randah Ribhi Hamadeh, Samer Hamidi, Abdullatif Husseini, Spencer Lewis James, Jost B. Jonas, Yousef Saleh Khader, Ejaz Ahmad Khan, Gulfaraz Khan, Jagdish Khubchandani, Niranjan Kissoon, Jacek A. Kopec, Ai Koyanagi, Barthelemy Kuate Defo, Heidi J. Larson, Asma Abdul Latif, Raimundas Lunevicius, Hassan Magdy Abd El Razek, Mohammed Magdy Abd El Razek, Reza Majdzadeh, Azeem Majeed, Reza Malekzadeh, Peter Memiah, Ziad A. Memish, Walter Mendoza, Desalegn Tadese Mengistu, Shafiu Mohammed, Srinivas Murthy, Josephine Wanjiku Ngunjiri, Felix Akpojene Ogbo, Farshad Pourmalek, Amir Radfar, Anwar Rafay, Vafa Rahimi-Movaghar, Rajesh Kumar Rai, Usha Ram, David Laith Rawaf, Salman Rawaf Salman, Andre M. N. Renzaho, Satar Rezaei, Gholamreza Roshandel, Mahdi Safdarian, Mohammad Ali Sahraian, Payman Salamati, Abdallah M. Samy, Juan Ramon Sanabria, Benn Sartorius, Sadaf G. Sepanlou, Masood Ali Shaikh, Mika Shigematsu, Badr H. A. Sobaih, Chandrashekhar T. Sreeramareddy, Bryan L. Sykes, Arash Tehrani-Banihashemi, Mohamad-Hani Temsah, Abdullah Sulieman Terkawi, Tenaw Yimer Tiruye, Roman Topor-Madry, Kingsley Nnanna Ukwaja, Stein Emil Vollset, Tolassa Wakayo, Andrea Werdecker, Charles Shey Wiysonge, Abdulhalik Workicho, Mohsen Yaghoubi, Mehdi Yaseri, Muluken Yenesew, Naohiro Yonemoto, Mustafa Z. Younis, Maysaa El Sayed Zaki, Bassel Zein, Sanjay Zodpey, Aisha O. Jumaan, Theo Vos, Simon I. Hay, Mohsen Naghavi, Christopher J. L. Murray, Ali H. Mokdad

Western Sydney University

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children's potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)"”the sum of years of life lost and years lived with disability"”for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018-124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4-19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640-79,486). DALYs per 100,000 ranged from 304 (95% UI 228-400) in Kuwait to 38,900 (95% UI 25,900-54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.

Original language	English
Pages (from-to)	S109-S121
Number of pages	13
Journal	International Journal of Public Health
Volume	63
Issue number	Supplement 1
DOIs	https://doi.org/10.1007/s00038-017-1008-z
Publication status	Published - 2018

Open Access - Access Right Statement

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Keywords

Middle East
diarrhea

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10.1007/s00038-017-1008-z

Cite this

Gbd 2015 Eastern Mediterranean Region Diarrhea Collaborators, X., Khalil, I., El Bcheraoui, C., Charara, R., Moradi-Lakeh, M., Afshin, A., Kassebaum, N. J., Collison, M., Chew, A., Krohn, K. J., Daoud, F., Colombara, D., Foreman, K. J., Godwin, W. W., Kutz, M., Mirarefin, M., Rao, P. C., Reiner, R., Troeger, C., ... Mokdad, A. H. (2018). Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015 : findings from the Global Burden of Disease 2015 Study. International Journal of Public Health, 63(Supplement 1), S109-S121. https://doi.org/10.1007/s00038-017-1008-z

@article{535a7a60b9e0452f9bcf10478e6da05c,

title = "Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015 : findings from the Global Burden of Disease 2015 Study",

abstract = "Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children's potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs){"}”the sum of years of life lost and years lived with disability{"}”for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018-124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4-19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640-79,486). DALYs per 100,000 ranged from 304 (95% UI 228-400) in Kuwait to 38,900 (95% UI 25,900-54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.",

keywords = "Middle East, diarrhea",

author = "{Gbd 2015 Eastern Mediterranean Region Diarrhea Collaborators}, x and Ibrahim Khalil and {El Bcheraoui}, Charbel and Raghid Charara and Maziar Moradi-Lakeh and Ashkan Afshin and Kassebaum, {Nicholas J.} and Michael Collison and Adrienne Chew and Krohn, {Kristopher J.} and Farah Daoud and Danny Colombara and Foreman, {Kyle J.} and Godwin, {William W.} and Michael Kutz and Mojde Mirarefin and Rao, {Puja C.} and Robert Reiner and Christopher Troeger and Haidong Wang and Abraha, {Haftom Niguse} and Remon Abu-Elyazeed and Abu-Raddad, {Laith J.} and {Ahmad Kiadaliri}, Aliasghar and Alireza Ahmadi and Ahmed, {Muktar Beshir} and Khurshid Alam and Reza Alizadeh-Navaei and Rajaa Al-Raddadi and Altirkawi, {Khalid A.} and Nelson Alvis-Guzman and Nahla Anber and Palwasha Anwari and Atey, {Tesfay Mehari} and Avokpaho, {Euripide Frinel G. Arthur} and Umar Bacha and Shahrzad Bazargan-Hejazi and Neeraj Bedi and Bensenor, {Isabela M.} and Adugnaw Berhane and Bessong, {Pascal Obong} and Beyene, {Addisu Shunu} and Bhutta, {Zulfiqar A.} and Buckle, {Geoffrey Colin} and Butt, {Zahid A.} and Hadi Danawi and Amare Deribew and Shirin Djalalinia and Manisha Dubey and Endries, {Aman Yesuf} and Babak Eshrati and Seyed-Mohammad Fereshtehnejad and Florian Fischer and Gebrehiwot, {Tsegaye Tewelde} and Gugnani, {Harish Chander} and Hamadeh, {Randah Ribhi} and Samer Hamidi and Abdullatif Husseini and James, {Spencer Lewis} and Jonas, {Jost B.} and Khader, {Yousef Saleh} and Khan, {Ejaz Ahmad} and Gulfaraz Khan and Jagdish Khubchandani and Niranjan Kissoon and Kopec, {Jacek A.} and Ai Koyanagi and {Kuate Defo}, Barthelemy and Larson, {Heidi J.} and Latif, {Asma Abdul} and Raimundas Lunevicius and {Magdy Abd El Razek}, Hassan and {Magdy Abd El Razek}, Mohammed and Reza Majdzadeh and Azeem Majeed and Reza Malekzadeh and Peter Memiah and Memish, {Ziad A.} and Walter Mendoza and Mengistu, {Desalegn Tadese} and Shafiu Mohammed and Srinivas Murthy and Ngunjiri, {Josephine Wanjiku} and Ogbo, {Felix Akpojene} and Farshad Pourmalek and Amir Radfar and Anwar Rafay and Vafa Rahimi-Movaghar and Rai, {Rajesh Kumar} and Usha Ram and Rawaf, {David Laith} and {Rawaf Salman}, Salman and Renzaho, {Andre M. N.} and Satar Rezaei and Gholamreza Roshandel and Mahdi Safdarian and Sahraian, {Mohammad Ali} and Payman Salamati and Samy, {Abdallah M.} and Sanabria, {Juan Ramon} and Benn Sartorius and Sepanlou, {Sadaf G.} and Shaikh, {Masood Ali} and Mika Shigematsu and Sobaih, {Badr H. A.} and Sreeramareddy, {Chandrashekhar T.} and Sykes, {Bryan L.} and Arash Tehrani-Banihashemi and Mohamad-Hani Temsah and Terkawi, {Abdullah Sulieman} and Tiruye, {Tenaw Yimer} and Roman Topor-Madry and Ukwaja, {Kingsley Nnanna} and Vollset, {Stein Emil} and Tolassa Wakayo and Andrea Werdecker and Wiysonge, {Charles Shey} and Abdulhalik Workicho and Mohsen Yaghoubi and Mehdi Yaseri and Muluken Yenesew and Naohiro Yonemoto and Younis, {Mustafa Z.} and Zaki, {Maysaa El Sayed} and Bassel Zein and Sanjay Zodpey and Jumaan, {Aisha O.} and Theo Vos and Hay, {Simon I.} and Mohsen Naghavi and Murray, {Christopher J. L.} and Mokdad, {Ali H.}",

year = "2018",

doi = "10.1007/s00038-017-1008-z",

language = "English",

volume = "63",

pages = "S109--S121",

journal = "International Journal of Public Health",

issn = "1661-8564",

publisher = "Frontiers Research Foundation",

number = "Supplement 1",

}

Gbd 2015 Eastern Mediterranean Region Diarrhea Collaborators, X, Khalil, I, El Bcheraoui, C, Charara, R, Moradi-Lakeh, M, Afshin, A, Kassebaum, NJ, Collison, M, Chew, A, Krohn, KJ, Daoud, F, Colombara, D, Foreman, KJ, Godwin, WW, Kutz, M, Mirarefin, M, Rao, PC, Reiner, R, Troeger, C, Wang, H, Abraha, HN, Abu-Elyazeed, R, Abu-Raddad, LJ, Ahmad Kiadaliri, A, Ahmadi, A, Ahmed, MB, Alam, K, Alizadeh-Navaei, R, Al-Raddadi, R, Altirkawi, KA, Alvis-Guzman, N, Anber, N, Anwari, P, Atey, TM, Avokpaho, EFGA, Bacha, U, Bazargan-Hejazi, S, Bedi, N, Bensenor, IM, Berhane, A, Bessong, PO, Beyene, AS, Bhutta, ZA, Buckle, GC, Butt, ZA, Danawi, H, Deribew, A, Djalalinia, S, Dubey, M, Endries, AY, Eshrati, B, Fereshtehnejad, S-M, Fischer, F, Gebrehiwot, TT, Gugnani, HC, Hamadeh, RR, Hamidi, S, Husseini, A, James, SL, Jonas, JB, Khader, YS, Khan, EA, Khan, G, Khubchandani, J, Kissoon, N, Kopec, JA, Koyanagi, A, Kuate Defo, B, Larson, HJ, Latif, AA, Lunevicius, R, Magdy Abd El Razek, H, Magdy Abd El Razek, M, Majdzadeh, R, Majeed, A, Malekzadeh, R, Memiah, P, Memish, ZA, Mendoza, W, Mengistu, DT, Mohammed, S, Murthy, S, Ngunjiri, JW, Ogbo, FA, Pourmalek, F, Radfar, A, Rafay, A, Rahimi-Movaghar, V, Rai, RK, Ram, U, Rawaf, DL, Rawaf Salman, S, Renzaho, AMN, Rezaei, S, Roshandel, G, Safdarian, M, Sahraian, MA, Salamati, P, Samy, AM, Sanabria, JR, Sartorius, B, Sepanlou, SG, Shaikh, MA, Shigematsu, M, Sobaih, BHA, Sreeramareddy, CT, Sykes, BL, Tehrani-Banihashemi, A, Temsah, M-H, Terkawi, AS, Tiruye, TY, Topor-Madry, R, Ukwaja, KN, Vollset, SE, Wakayo, T, Werdecker, A, Wiysonge, CS, Workicho, A, Yaghoubi, M, Yaseri, M, Yenesew, M, Yonemoto, N, Younis, MZ, Zaki, MES, Zein, B, Zodpey, S, Jumaan, AO, Vos, T, Hay, SI, Naghavi, M, Murray, CJL & Mokdad, AH 2018, 'Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015 : findings from the Global Burden of Disease 2015 Study', International Journal of Public Health, vol. 63, no. Supplement 1, pp. S109-S121. https://doi.org/10.1007/s00038-017-1008-z

Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015 : findings from the Global Burden of Disease 2015 Study. / Gbd 2015 Eastern Mediterranean Region Diarrhea Collaborators, x; Khalil, Ibrahim; El Bcheraoui, Charbel et al.
In: International Journal of Public Health, Vol. 63, No. Supplement 1, 2018, p. S109-S121.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015 : findings from the Global Burden of Disease 2015 Study

AU - Gbd 2015 Eastern Mediterranean Region Diarrhea Collaborators, x

AU - Khalil, Ibrahim

AU - El Bcheraoui, Charbel

AU - Charara, Raghid

AU - Moradi-Lakeh, Maziar

AU - Afshin, Ashkan

AU - Kassebaum, Nicholas J.

AU - Collison, Michael

AU - Chew, Adrienne

AU - Krohn, Kristopher J.

AU - Daoud, Farah

AU - Colombara, Danny

AU - Foreman, Kyle J.

AU - Godwin, William W.

AU - Kutz, Michael

AU - Mirarefin, Mojde

AU - Rao, Puja C.

AU - Reiner, Robert

AU - Troeger, Christopher

AU - Wang, Haidong

AU - Abraha, Haftom Niguse

AU - Abu-Elyazeed, Remon

AU - Abu-Raddad, Laith J.

AU - Ahmad Kiadaliri, Aliasghar

AU - Ahmadi, Alireza

AU - Ahmed, Muktar Beshir

AU - Alam, Khurshid

AU - Alizadeh-Navaei, Reza

AU - Al-Raddadi, Rajaa

AU - Altirkawi, Khalid A.

AU - Alvis-Guzman, Nelson

AU - Anber, Nahla

AU - Anwari, Palwasha

AU - Atey, Tesfay Mehari

AU - Avokpaho, Euripide Frinel G. Arthur

AU - Bacha, Umar

AU - Bazargan-Hejazi, Shahrzad

AU - Bedi, Neeraj

AU - Bensenor, Isabela M.

AU - Berhane, Adugnaw

AU - Bessong, Pascal Obong

AU - Beyene, Addisu Shunu

AU - Bhutta, Zulfiqar A.

AU - Buckle, Geoffrey Colin

AU - Butt, Zahid A.

AU - Danawi, Hadi

AU - Deribew, Amare

AU - Djalalinia, Shirin

AU - Dubey, Manisha

AU - Endries, Aman Yesuf

AU - Eshrati, Babak

AU - Fereshtehnejad, Seyed-Mohammad

AU - Fischer, Florian

AU - Gebrehiwot, Tsegaye Tewelde

AU - Gugnani, Harish Chander

AU - Hamadeh, Randah Ribhi

AU - Hamidi, Samer

AU - Husseini, Abdullatif

AU - James, Spencer Lewis

AU - Jonas, Jost B.

AU - Khader, Yousef Saleh

AU - Khan, Ejaz Ahmad

AU - Khan, Gulfaraz

AU - Khubchandani, Jagdish

AU - Kissoon, Niranjan

AU - Kopec, Jacek A.

AU - Koyanagi, Ai

AU - Kuate Defo, Barthelemy

AU - Larson, Heidi J.

AU - Latif, Asma Abdul

AU - Lunevicius, Raimundas

AU - Magdy Abd El Razek, Hassan

AU - Magdy Abd El Razek, Mohammed

AU - Majdzadeh, Reza

AU - Majeed, Azeem

AU - Malekzadeh, Reza

AU - Memiah, Peter

AU - Memish, Ziad A.

AU - Mendoza, Walter

AU - Mengistu, Desalegn Tadese

AU - Mohammed, Shafiu

AU - Murthy, Srinivas

AU - Ngunjiri, Josephine Wanjiku

AU - Ogbo, Felix Akpojene

AU - Pourmalek, Farshad

AU - Radfar, Amir

AU - Rafay, Anwar

AU - Rahimi-Movaghar, Vafa

AU - Rai, Rajesh Kumar

AU - Ram, Usha

AU - Rawaf, David Laith

AU - Rawaf Salman, Salman

AU - Renzaho, Andre M. N.

AU - Rezaei, Satar

AU - Roshandel, Gholamreza

AU - Safdarian, Mahdi

AU - Sahraian, Mohammad Ali

AU - Salamati, Payman

AU - Samy, Abdallah M.

AU - Sanabria, Juan Ramon

AU - Sartorius, Benn

AU - Sepanlou, Sadaf G.

AU - Shaikh, Masood Ali

AU - Shigematsu, Mika

AU - Sobaih, Badr H. A.

AU - Sreeramareddy, Chandrashekhar T.

AU - Sykes, Bryan L.

AU - Tehrani-Banihashemi, Arash

AU - Temsah, Mohamad-Hani

AU - Terkawi, Abdullah Sulieman

AU - Tiruye, Tenaw Yimer

AU - Topor-Madry, Roman

AU - Ukwaja, Kingsley Nnanna

AU - Vollset, Stein Emil

AU - Wakayo, Tolassa

AU - Werdecker, Andrea

AU - Wiysonge, Charles Shey

AU - Workicho, Abdulhalik

AU - Yaghoubi, Mohsen

AU - Yaseri, Mehdi

AU - Yenesew, Muluken

AU - Yonemoto, Naohiro

AU - Younis, Mustafa Z.

AU - Zaki, Maysaa El Sayed

AU - Zein, Bassel

AU - Zodpey, Sanjay

AU - Jumaan, Aisha O.

AU - Vos, Theo

AU - Hay, Simon I.

AU - Naghavi, Mohsen

AU - Murray, Christopher J. L.

AU - Mokdad, Ali H.

PY - 2018

Y1 - 2018

N2 - Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children's potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)"”the sum of years of life lost and years lived with disability"”for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018-124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4-19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640-79,486). DALYs per 100,000 ranged from 304 (95% UI 228-400) in Kuwait to 38,900 (95% UI 25,900-54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.

AB - Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children's potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)"”the sum of years of life lost and years lived with disability"”for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018-124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4-19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640-79,486). DALYs per 100,000 ranged from 304 (95% UI 228-400) in Kuwait to 38,900 (95% UI 25,900-54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.

KW - Middle East

KW - diarrhea

UR - http://hdl.handle.net/1959.7/uws:43054

U2 - 10.1007/s00038-017-1008-z

DO - 10.1007/s00038-017-1008-z

M3 - Article

SN - 1661-8564

SN - 1661-8556

VL - 63

SP - S109-S121

JO - International Journal of Public Health

JF - International Journal of Public Health

IS - Supplement 1

ER -

Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015 : findings from the Global Burden of Disease 2015 Study

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