Abstract
Human skin is innervated by two major classes of sensory nerve fibres (afferents) – myelinated large-diameter A-fibres and small-diameter unmyelinated C-fibres. A-beta subclass afferents innervating innocuous (low-threshold) mechanoreceptors in the skin are responsible for discriminative touch, allowing us to perceive various properties of objects, understand the environment and effectively control our movement. C-fibre afferents are typically mentioned in relation to nociception or pain perception.
| Original language | English |
|---|---|
| Pages (from-to) | 4441-4442 |
| Number of pages | 2 |
| Journal | Journal of Physiology |
| Volume | 603 |
| Issue number | 16 |
| DOIs | |
| Publication status | Published - Aug 2025 |
| Externally published | Yes |
Keywords
- affective touch
- C-LTMR
- C-tactile afferents
- hair follicle
- mechanoreceptors
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