Cancer and cancer-related fatigue and the interrelationships with depression, stress, and inflammation

Daniel Weber; Kylie O’Brien

doi:10.1177/2156587216676122

Cancer and cancer-related fatigue and the interrelationships with depression, stress, and inflammation

Daniel Weber
, Kylie O’Brien

Research output: Contribution to journal › Article › peer-review

91 Citations (Scopus)

Abstract

Cancer-related fatigue (CRF) is a common symptom experienced in cancer patients. Depression, anxiety, and stress are associated with cancer. Depression and anxiety are also associated with CRF. At the cellular level, much is known about the impact of stress on the body generally, and its potential role in cancer. Stress, anxiety, and depression have been found to depress the immune system. Depression and stress have also been found to create inflammatory changes in the body and there is emerging evidence that inflammation is involved in cancer pathogenesis and in CRF. This article examines the relationships between stress, anxiety, depression, and cancer; relationships between anxiety and depression and CRF; and what happens at the cellular level, including impact on the immune system and emerging evidence of the role of inflammation in CRF. It also reports on research in relation to some Chinese herbal medicines that may be used to treat CRF.

Original language	English
Pages (from-to)	502-512
Number of pages	11
Journal	Journal of Evidence-Based Complementary and Alternative Medicine
Volume	22
Issue number	3
DOIs	https://doi.org/10.1177/2156587216676122
Publication status	Published - 2017

Open Access - Access Right Statement

Creative Commons CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

cancer
depression, mental
fatigue
herbs
inflammation
medicine, Chinese
stress (psychology)
therapeutic use

Access to Document

10.1177/2156587216676122

Cite this

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title = "Cancer and cancer-related fatigue and the interrelationships with depression, stress, and inflammation",

abstract = "Cancer-related fatigue (CRF) is a common symptom experienced in cancer patients. Depression, anxiety, and stress are associated with cancer. Depression and anxiety are also associated with CRF. At the cellular level, much is known about the impact of stress on the body generally, and its potential role in cancer. Stress, anxiety, and depression have been found to depress the immune system. Depression and stress have also been found to create inflammatory changes in the body and there is emerging evidence that inflammation is involved in cancer pathogenesis and in CRF. This article examines the relationships between stress, anxiety, depression, and cancer; relationships between anxiety and depression and CRF; and what happens at the cellular level, including impact on the immune system and emerging evidence of the role of inflammation in CRF. It also reports on research in relation to some Chinese herbal medicines that may be used to treat CRF.",

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T1 - Cancer and cancer-related fatigue and the interrelationships with depression, stress, and inflammation

AU - Weber, Daniel

AU - O’Brien, Kylie

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AB - Cancer-related fatigue (CRF) is a common symptom experienced in cancer patients. Depression, anxiety, and stress are associated with cancer. Depression and anxiety are also associated with CRF. At the cellular level, much is known about the impact of stress on the body generally, and its potential role in cancer. Stress, anxiety, and depression have been found to depress the immune system. Depression and stress have also been found to create inflammatory changes in the body and there is emerging evidence that inflammation is involved in cancer pathogenesis and in CRF. This article examines the relationships between stress, anxiety, depression, and cancer; relationships between anxiety and depression and CRF; and what happens at the cellular level, including impact on the immune system and emerging evidence of the role of inflammation in CRF. It also reports on research in relation to some Chinese herbal medicines that may be used to treat CRF.

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KW - depression, mental

KW - fatigue

KW - herbs

KW - inflammation

KW - medicine, Chinese

KW - stress (psychology)

KW - therapeutic use

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:41370

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DO - 10.1177/2156587216676122

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JO - Journal of Evidence-Based Complementary and Alternative Medicine

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Cancer and cancer-related fatigue and the interrelationships with depression, stress, and inflammation

Abstract

Open Access - Access Right Statement

UN SDGs

Keywords

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