Carriage of an ACME II variant may have contributed to methicillin- resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia

B. A. Espedido; J. A. Steen; T. Barbagiannakos; J. Mercer; D. L. Paterson; S. M. Grimmond; M. A. Cooper; I. B. Gosbell; S. J. van Hal; S. O. Jensen

doi:10.1128/AAC.00013-12

Carriage of an ACME II variant may have contributed to methicillin- resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia

B. A. Espedido, J. A. Steen, T. Barbagiannakos, J. Mercer, D. L. Paterson, S. M. Grimmond, M. A. Cooper, I. B. Gosbell, S. J. van Hal, S. O. Jensen

School of Medicine

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Approximately 39% of methicillin-resistant Staphylococcus aureus (MRSA) sequence type 239 (ST239)-like bloodstream isolates from Liverpool Hospital (obtained between 1997 and 2008) carry an arginine catabolic mobile element (ACME). Whole-genome sequencing revealed that an ACME II variant is located between orfX and SCCmec III, and based on pulsed-field gel electrophoresis patterns and temporal relationships of all ST239-like isolates (n = 360), ACME carriage may have contributed to subpulsotype strain replacement.

Original language	English
Pages (from-to)	3380-3383
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	56
Issue number	6
DOIs	https://doi.org/10.1128/AAC.00013-12
Publication status	Published - 2012

Keywords

Staphylococcus aureus
bacteria
bacterial strain
blood flow
gene sequence
genes
nucleotide sequence
polymerase chain reaction
protein

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/AAC.00013-12

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Espedido, B. A., Steen, J. A., Barbagiannakos, T., Mercer, J., Paterson, D. L., Grimmond, S. M., Cooper, M. A., Gosbell, I. B., Hal, S. J. V., & Jensen, S. O. (2012). Carriage of an ACME II variant may have contributed to methicillin- resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia. Antimicrobial Agents and Chemotherapy, 56(6), 3380-3383. https://doi.org/10.1128/AAC.00013-12

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title = "Carriage of an ACME II variant may have contributed to methicillin- resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia",

abstract = "Approximately 39% of methicillin-resistant Staphylococcus aureus (MRSA) sequence type 239 (ST239)-like bloodstream isolates from Liverpool Hospital (obtained between 1997 and 2008) carry an arginine catabolic mobile element (ACME). Whole-genome sequencing revealed that an ACME II variant is located between orfX and SCCmec III, and based on pulsed-field gel electrophoresis patterns and temporal relationships of all ST239-like isolates (n = 360), ACME carriage may have contributed to subpulsotype strain replacement.",

keywords = "Staphylococcus aureus, bacteria, bacterial strain, blood flow, gene sequence, genes, nucleotide sequence, polymerase chain reaction, protein",

author = "Espedido, {B. A.} and Steen, {J. A.} and T. Barbagiannakos and J. Mercer and Paterson, {D. L.} and Grimmond, {S. M.} and Cooper, {M. A.} and Gosbell, {I. B.} and Hal, {S. J. van} and Jensen, {S. O.}",

year = "2012",

doi = "10.1128/AAC.00013-12",

language = "English",

volume = "56",

pages = "3380--3383",

journal = "Antimicrobial Agents and Chemotherapy",

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publisher = "American Society for Microbiology",

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}

Espedido, BA, Steen, JA, Barbagiannakos, T, Mercer, J, Paterson, DL, Grimmond, SM, Cooper, MA, Gosbell, IB, Hal, SJV & Jensen, SO 2012, 'Carriage of an ACME II variant may have contributed to methicillin- resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia', Antimicrobial Agents and Chemotherapy, vol. 56, no. 6, pp. 3380-3383. https://doi.org/10.1128/AAC.00013-12

Carriage of an ACME II variant may have contributed to methicillin- resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia. / Espedido, B. A.; Steen, J. A.; Barbagiannakos, T. et al.
In: Antimicrobial Agents and Chemotherapy, Vol. 56, No. 6, 2012, p. 3380-3383.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Carriage of an ACME II variant may have contributed to methicillin- resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia

AU - Espedido, B. A.

AU - Steen, J. A.

AU - Barbagiannakos, T.

AU - Mercer, J.

AU - Paterson, D. L.

AU - Grimmond, S. M.

AU - Cooper, M. A.

AU - Gosbell, I. B.

AU - Hal, S. J. van

AU - Jensen, S. O.

PY - 2012

Y1 - 2012

N2 - Approximately 39% of methicillin-resistant Staphylococcus aureus (MRSA) sequence type 239 (ST239)-like bloodstream isolates from Liverpool Hospital (obtained between 1997 and 2008) carry an arginine catabolic mobile element (ACME). Whole-genome sequencing revealed that an ACME II variant is located between orfX and SCCmec III, and based on pulsed-field gel electrophoresis patterns and temporal relationships of all ST239-like isolates (n = 360), ACME carriage may have contributed to subpulsotype strain replacement.

AB - Approximately 39% of methicillin-resistant Staphylococcus aureus (MRSA) sequence type 239 (ST239)-like bloodstream isolates from Liverpool Hospital (obtained between 1997 and 2008) carry an arginine catabolic mobile element (ACME). Whole-genome sequencing revealed that an ACME II variant is located between orfX and SCCmec III, and based on pulsed-field gel electrophoresis patterns and temporal relationships of all ST239-like isolates (n = 360), ACME carriage may have contributed to subpulsotype strain replacement.

KW - Staphylococcus aureus

KW - bacteria

KW - bacterial strain

KW - blood flow

KW - gene sequence

KW - genes

KW - nucleotide sequence

KW - polymerase chain reaction

KW - protein

UR - http://handle.uws.edu.au:8081/1959.7/517150

U2 - 10.1128/AAC.00013-12

DO - 10.1128/AAC.00013-12

M3 - Article

C2 - 22391530

SN - 0066-4804

VL - 56

SP - 3380

EP - 3383

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 6

ER -

Carriage of an ACME II variant may have contributed to methicillin- resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia

Abstract

Keywords

UN SDGs

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