TY - JOUR
T1 - Cell, gene and regenerative therapies in cardiovascular disease
T2 - charting a course from the research bench to clinical utility
AU - Gregory, Ann T.
AU - Pepe, Salvatore
AU - Denniss, A. Robert
AU - Kizana, Eddy
AU - Chong, James J.H.
PY - 2023/7
Y1 - 2023/7
N2 - We all know of the huge (and increasing) global burden of cardiovascular disease, and of the research efforts in so many disciplines to minimise the onset and impact of cardiac injury from inherited and acquired disease. In the areas of cardiac cell and gene therapy and tissue regeneration, early results of two or three decades ago fell short of their promise for one reason or another, or their priority lessened when other proven treatments became available.
AB - We all know of the huge (and increasing) global burden of cardiovascular disease, and of the research efforts in so many disciplines to minimise the onset and impact of cardiac injury from inherited and acquired disease. In the areas of cardiac cell and gene therapy and tissue regeneration, early results of two or three decades ago fell short of their promise for one reason or another, or their priority lessened when other proven treatments became available.
KW - Adeno-associated virus
KW - Cardiac cell therapy
KW - Cardiovascular disease
KW - Exosomes
KW - Gene therapy
KW - Tissue regeneration
UR - http://www.scopus.com/inward/record.url?scp=85166555945&partnerID=8YFLogxK
UR - https://go.openathens.net/redirector/westernsydney.edu.au?url=https://doi.org/10.1016/j.hlc.2023.07.003
U2 - 10.1016/j.hlc.2023.07.003
DO - 10.1016/j.hlc.2023.07.003
M3 - Article
C2 - 37536880
AN - SCOPUS:85166555945
SN - 1443-9506
VL - 32
SP - 765
EP - 768
JO - Heart, Lung and Circulation
JF - Heart, Lung and Circulation
IS - 7
ER -