Cell, gene and regenerative therapies in cardiovascular disease: charting a course from the research bench to clinical utility

Ann T. Gregory; Salvatore Pepe; A. Robert Denniss; Eddy Kizana; James J.H. Chong

doi:10.1016/j.hlc.2023.07.003

Cell, gene and regenerative therapies in cardiovascular disease: charting a course from the research bench to clinical utility

Ann T. Gregory
, Salvatore Pepe
, A. Robert Denniss
, Eddy Kizana
, James J.H. Chong

School of Medicine

Heart, Lung and Circulation
Royal Children's Hospital Melbourne
University of Melbourne
Westmead Hospital
The University of Sydney
Westmead Institute for Medical Research

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

We all know of the huge (and increasing) global burden of cardiovascular disease, and of the research efforts in so many disciplines to minimise the onset and impact of cardiac injury from inherited and acquired disease. In the areas of cardiac cell and gene therapy and tissue regeneration, early results of two or three decades ago fell short of their promise for one reason or another, or their priority lessened when other proven treatments became available.

Original language	English
Pages (from-to)	765-768
Number of pages	4
Journal	Heart, Lung and Circulation
Volume	32
Issue number	7
DOIs	https://doi.org/10.1016/j.hlc.2023.07.003
Publication status	Published - Jul 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adeno-associated virus
Cardiac cell therapy
Cardiovascular disease
Exosomes
Gene therapy
Tissue regeneration

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10.1016/j.hlc.2023.07.003

Cite this

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title = "Cell, gene and regenerative therapies in cardiovascular disease: charting a course from the research bench to clinical utility",

abstract = "We all know of the huge (and increasing) global burden of cardiovascular disease, and of the research efforts in so many disciplines to minimise the onset and impact of cardiac injury from inherited and acquired disease. In the areas of cardiac cell and gene therapy and tissue regeneration, early results of two or three decades ago fell short of their promise for one reason or another, or their priority lessened when other proven treatments became available.",

keywords = "Adeno-associated virus, Cardiac cell therapy, Cardiovascular disease, Exosomes, Gene therapy, Tissue regeneration",

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AU - Pepe, Salvatore

AU - Denniss, A. Robert

AU - Kizana, Eddy

AU - Chong, James J.H.

PY - 2023/7

Y1 - 2023/7

N2 - We all know of the huge (and increasing) global burden of cardiovascular disease, and of the research efforts in so many disciplines to minimise the onset and impact of cardiac injury from inherited and acquired disease. In the areas of cardiac cell and gene therapy and tissue regeneration, early results of two or three decades ago fell short of their promise for one reason or another, or their priority lessened when other proven treatments became available.

AB - We all know of the huge (and increasing) global burden of cardiovascular disease, and of the research efforts in so many disciplines to minimise the onset and impact of cardiac injury from inherited and acquired disease. In the areas of cardiac cell and gene therapy and tissue regeneration, early results of two or three decades ago fell short of their promise for one reason or another, or their priority lessened when other proven treatments became available.

KW - Adeno-associated virus

KW - Cardiac cell therapy

KW - Cardiovascular disease

KW - Exosomes

KW - Gene therapy

KW - Tissue regeneration

UR - https://www.scopus.com/pages/publications/85166555945

UR - https://go.openathens.net/redirector/westernsydney.edu.au?url=https://doi.org/10.1016/j.hlc.2023.07.003

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SN - 1443-9506

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JF - Heart, Lung and Circulation

IS - 7

ER -

Cell, gene and regenerative therapies in cardiovascular disease: charting a course from the research bench to clinical utility

Abstract

UN SDGs

Keywords

Access to Document

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