Chronic arsenic exposure and type 2 diabetes : a meta-analysis

Tanvir Abir; Hossain Akbar; Rahman Bayzidur; Islam Rafiqul; Milton Abul Hasnat

Chronic arsenic exposure and type 2 diabetes : a meta-analysis

Tanvir Abir
, Hossain Akbar
, Rahman Bayzidur
, Islam Rafiqul
, Milton Abul Hasnat

Research output: Chapter in Book / Conference Paper › Conference Paper › peer-review

Abstract

Chronic exposure to inorganic arsenic in drinking water has been associated with Type 2 Diabetes (T2D). However, the association is still inconclusive. We incorporated 33 studies in the analysis including 13 cross-sectional, 6 case-control and 4 cohort studies reporting Odds Ratio (OR), 6 cross-sectional and cohort studies reporting Relative Risk (RR) and 3 mortality studies reporting Standardized Mortality Ratio (SMR). The pooled OR estimate was 1.76 (95% CI: 1.43, 2.17), pooled RR was 1.17 (95% CI: 0.95, 1.45) and pooled SMR was 0.79 (95% CI: 0.59, 1.06), and the overall pooled estimate was 1.55 (95% CI: 1.27, 1.88). The study heterogeneity was very high (I2 = 97% for case-control studies, 47% for cohort studies, and overall 98%). Because of the very high heterogeneity and non-significant results from cohort studies, this analysis provides a limited evidence for an association between arsenic and Type 2 Diabetes (T2D) that needs further validation.

Original language	English
Title of host publication	One Century of the Discovery of Arsenicosis in Latin America (1914-2014) As2014: Proceedings of the 5th International Congress on Arsenic in the Environment, Buenos Aires, Argentina, 11-16 May 2014
Publisher	CRC Press
Pages	590-591
Number of pages	2
ISBN (Print)	9781138001411
Publication status	Published - 2014
Event	International Congress on Arsenic in the Environment - Duration: 11 May 2014 → …

Conference

Conference	International Congress on Arsenic in the Environment
Period	11/05/14 → …

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 6 Clean Water and Sanitation

Keywords

Latin America
arsenic
drinking water
non-insulin-dependent diabetes
risk assessment

Cite this

@inproceedings{ecb96b62d9134cf4aae6ae176ee6fcb8,

title = "Chronic arsenic exposure and type 2 diabetes : a meta-analysis",

abstract = "Chronic exposure to inorganic arsenic in drinking water has been associated with Type 2 Diabetes (T2D). However, the association is still inconclusive. We incorporated 33 studies in the analysis including 13 cross-sectional, 6 case-control and 4 cohort studies reporting Odds Ratio (OR), 6 cross-sectional and cohort studies reporting Relative Risk (RR) and 3 mortality studies reporting Standardized Mortality Ratio (SMR). The pooled OR estimate was 1.76 (95\% CI: 1.43, 2.17), pooled RR was 1.17 (95\% CI: 0.95, 1.45) and pooled SMR was 0.79 (95\% CI: 0.59, 1.06), and the overall pooled estimate was 1.55 (95\% CI: 1.27, 1.88). The study heterogeneity was very high (I2 = 97\% for case-control studies, 47\% for cohort studies, and overall 98\%). Because of the very high heterogeneity and non-significant results from cohort studies, this analysis provides a limited evidence for an association between arsenic and Type 2 Diabetes (T2D) that needs further validation.",

keywords = "Latin America, arsenic, drinking water, non-insulin-dependent diabetes, risk assessment",

author = "Tanvir Abir and Hossain Akbar and Rahman Bayzidur and Islam Rafiqul and Hasnat, \{Milton Abul\}",

year = "2014",

language = "English",

isbn = "9781138001411",

pages = "590--591",

booktitle = "One Century of the Discovery of Arsenicosis in Latin America (1914-2014) As2014: Proceedings of the 5th International Congress on Arsenic in the Environment, Buenos Aires, Argentina, 11-16 May 2014",

publisher = "CRC Press",

note = "International Congress on Arsenic in the Environment ; Conference date: 11-05-2014",

}

Abir, T, Akbar, H, Bayzidur, R, Rafiqul, I & Hasnat, MA 2014, Chronic arsenic exposure and type 2 diabetes : a meta-analysis. in One Century of the Discovery of Arsenicosis in Latin America (1914-2014) As2014: Proceedings of the 5th International Congress on Arsenic in the Environment, Buenos Aires, Argentina, 11-16 May 2014. CRC Press, pp. 590-591, International Congress on Arsenic in the Environment, 11/05/14.

Chronic arsenic exposure and type 2 diabetes : a meta-analysis. / Abir, Tanvir; Akbar, Hossain; Bayzidur, Rahman et al.
One Century of the Discovery of Arsenicosis in Latin America (1914-2014) As2014: Proceedings of the 5th International Congress on Arsenic in the Environment, Buenos Aires, Argentina, 11-16 May 2014. CRC Press, 2014. p. 590-591.

Research output: Chapter in Book / Conference Paper › Conference Paper › peer-review

TY - GEN

T1 - Chronic arsenic exposure and type 2 diabetes : a meta-analysis

AU - Abir, Tanvir

AU - Akbar, Hossain

AU - Bayzidur, Rahman

AU - Rafiqul, Islam

AU - Hasnat, Milton Abul

PY - 2014

Y1 - 2014

N2 - Chronic exposure to inorganic arsenic in drinking water has been associated with Type 2 Diabetes (T2D). However, the association is still inconclusive. We incorporated 33 studies in the analysis including 13 cross-sectional, 6 case-control and 4 cohort studies reporting Odds Ratio (OR), 6 cross-sectional and cohort studies reporting Relative Risk (RR) and 3 mortality studies reporting Standardized Mortality Ratio (SMR). The pooled OR estimate was 1.76 (95% CI: 1.43, 2.17), pooled RR was 1.17 (95% CI: 0.95, 1.45) and pooled SMR was 0.79 (95% CI: 0.59, 1.06), and the overall pooled estimate was 1.55 (95% CI: 1.27, 1.88). The study heterogeneity was very high (I2 = 97% for case-control studies, 47% for cohort studies, and overall 98%). Because of the very high heterogeneity and non-significant results from cohort studies, this analysis provides a limited evidence for an association between arsenic and Type 2 Diabetes (T2D) that needs further validation.

AB - Chronic exposure to inorganic arsenic in drinking water has been associated with Type 2 Diabetes (T2D). However, the association is still inconclusive. We incorporated 33 studies in the analysis including 13 cross-sectional, 6 case-control and 4 cohort studies reporting Odds Ratio (OR), 6 cross-sectional and cohort studies reporting Relative Risk (RR) and 3 mortality studies reporting Standardized Mortality Ratio (SMR). The pooled OR estimate was 1.76 (95% CI: 1.43, 2.17), pooled RR was 1.17 (95% CI: 0.95, 1.45) and pooled SMR was 0.79 (95% CI: 0.59, 1.06), and the overall pooled estimate was 1.55 (95% CI: 1.27, 1.88). The study heterogeneity was very high (I2 = 97% for case-control studies, 47% for cohort studies, and overall 98%). Because of the very high heterogeneity and non-significant results from cohort studies, this analysis provides a limited evidence for an association between arsenic and Type 2 Diabetes (T2D) that needs further validation.

KW - Latin America

KW - arsenic

KW - drinking water

KW - non-insulin-dependent diabetes

KW - risk assessment

UR - http://handle.uws.edu.au:8081/1959.7/565489

UR - http://www.as2014.com.ar/home.html

M3 - Conference Paper

SN - 9781138001411

SP - 590

EP - 591

BT - One Century of the Discovery of Arsenicosis in Latin America (1914-2014) As2014: Proceedings of the 5th International Congress on Arsenic in the Environment, Buenos Aires, Argentina, 11-16 May 2014

PB - CRC Press

T2 - International Congress on Arsenic in the Environment

Y2 - 11 May 2014

ER -

Chronic arsenic exposure and type 2 diabetes : a meta-analysis

Abstract

Conference

UN SDGs

Keywords

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