Chronic fatigue syndrome : progress and possibilities

Carolina X. Sandler, Andrew R. Lloyd

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)

Abstract

Chronic fatigue syndrome (CFS) is an enigmatic clinical entity which challenges patients, health care providers and researchers alike.1 The diagnosis is sometimes avoided by medical practitioners, leaving patients in diagnostic limbo and prone to non-evidence-based labels and potentially harmful treatments. This quandary reflects the lack of a diagnostic test, validated biomarker, clear pathophysiology or curative treatment. We retrieved publications from MEDLINE, PsycINFO, EMBASE, Cochrane and PubMed databases from 1988 to 2019 to consider aspects of clinical decision making in the diagnosis, assessment of prognosis, and management of CFS; provide an update on understanding of CFS pathophysiology; and identify priorities for improved care of patients with CFS and for future research. This review focuses on adult populations, but the condition also affects children and adolescents (reviewed elsewhere).
Original languageEnglish
Pages (from-to)428-433
Number of pages6
JournalMedical Journal of Australia
Volume212
Issue number9
DOIs
Publication statusPublished - 2020

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