Clinical practice of allergen immunotherapy for allergic rhinoconjunctivitis and asthma : an expert panel report

Moisés A. Calderon, Susan Waserman, David I. Bernstein, Pascal Demoly, Jo Douglass, Remi Gagnon, Constance H. Katelaris, Harold Kim, Harold S. Nelson, Yoshitaka Okamoto, Kimihiro Okubo, J. Christian Virchow, Lawrence DuBuske, Thomas B. Casale, G. Walter Canonica, Hendrik Nolte

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

Allergen immunotherapy (AIT) reduces symptoms and medication use associated with allergic rhinitis with or without conjunctivitis and allergic asthma. Although several AIT guidelines exist, there remain unanswered questions about AIT that are relevant to everyday practice. Our objective was to prepare an evidence-based overview addressing the practical aspects of AIT in clinical practice based on published evidence and the experience of international experts in the field. Topics covered include interpretation and translation of clinical trial data into everyday clinical practice (eg, allergen doses and treatment duration), assessment of risk and treatment of local and systemic allergic reactions, recommendations for improvement of AIT guidelines, and identification of appropriate data for seeking regulatory approval, to name a few. Many informational gaps in AIT practice need further evaluation as products and practices evolve.
Original languageEnglish
Pages (from-to)2920-2936
Number of pages17
JournalJournal of Allergy and Clinical Immunology: In Practice
Volume8
Issue number9
DOIs
Publication statusPublished - 2020

Keywords

  • allergy
  • asthma
  • hay fever
  • immunotherapy

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