Combination treatment with insulin sensitisers improves the antiviral effect of interferon against hepatitis C virus

S. A. Read; J. George; M. W. Douglas

Combination treatment with insulin sensitisers improves the antiviral effect of interferon against hepatitis C virus

S. A. Read, J. George, M. W. Douglas

Western Sydney University

Research output: Contribution to journal › Article › peer-review

Abstract

Pegylated interferon (IFN) in combination with ribavirin is currently the standard of care for the treatment of hepatitis C virus (HCV) infection, but achieves a sustained viral response in only 50%-60% of patients. Interestingly, patients with HCV genotypes that are more resistant to treatment also demonstrate insulin resistance. Thus we sought to examine the effects of insulin sensitisers on the response of HCV to IFN.

Original language	English
Pages (from-to)	A121-A121
Number of pages	1
Journal	Journal of Gastroenterology and Hepatology
Volume	25
Issue number	Suppl. S3
Publication status	Published - 2010

Keywords

hepatitis C virus
intererfon
antiviral agents

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Combination treatment with insulin sensitisers improves the antiviral effect of interferon against hepatitis C virus",

abstract = "Pegylated interferon (IFN) in combination with ribavirin is currently the standard of care for the treatment of hepatitis C virus (HCV) infection, but achieves a sustained viral response in only 50%-60% of patients. Interestingly, patients with HCV genotypes that are more resistant to treatment also demonstrate insulin resistance. Thus we sought to examine the effects of insulin sensitisers on the response of HCV to IFN.",

keywords = "hepatitis C virus, intererfon, antiviral agents",

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year = "2010",

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volume = "25",

pages = "A121--A121",

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TY - JOUR

T1 - Combination treatment with insulin sensitisers improves the antiviral effect of interferon against hepatitis C virus

AU - Read, S. A.

AU - George, J.

AU - Douglas, M. W.

PY - 2010

Y1 - 2010

N2 - Pegylated interferon (IFN) in combination with ribavirin is currently the standard of care for the treatment of hepatitis C virus (HCV) infection, but achieves a sustained viral response in only 50%-60% of patients. Interestingly, patients with HCV genotypes that are more resistant to treatment also demonstrate insulin resistance. Thus we sought to examine the effects of insulin sensitisers on the response of HCV to IFN.

AB - Pegylated interferon (IFN) in combination with ribavirin is currently the standard of care for the treatment of hepatitis C virus (HCV) infection, but achieves a sustained viral response in only 50%-60% of patients. Interestingly, patients with HCV genotypes that are more resistant to treatment also demonstrate insulin resistance. Thus we sought to examine the effects of insulin sensitisers on the response of HCV to IFN.

KW - hepatitis C virus

KW - intererfon

KW - antiviral agents

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:45270

M3 - Article

SN - 0815-9319

VL - 25

SP - A121-A121

JO - Journal of Gastroenterology and Hepatology

JF - Journal of Gastroenterology and Hepatology

IS - Suppl. S3

ER -

Combination treatment with insulin sensitisers improves the antiviral effect of interferon against hepatitis C virus

Abstract

Keywords

UN SDGs

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