Common problems and artifacts encountered in solution-state NMR experiments

NMR experiments contain many parameters that need to be set properly to produce spectra free from errors and artifacts. Modern NMR spectrometers nowadays incorporate standard experimental templates with ideal parameters that suit many common samples. These address many of the problems associated with most parameters but because of the variety of samples and various experiments that can be performed, the obtained spectra can be less than ideal displaying unwanted artifacts and inaccurate spectral properties. In this paper, some of the most common problems and artifacts in NMR experiments are presented and solutions discussed.