Complement-mediated thrombotic microangiopathy on a background of Alport syndrome: a case report

Craig Peter Coorey, Theo de Malmanche, Angela Chou, Martin Feddersen

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Abstract

Here we present a case of complement-mediated thrombotic microangiopathy (TMA) in a patient who has a background of Stage 5 chronic kidney disease secondary to Alport syndrome. We explain our approach to the diagnosis of TMA, especially the reliance on non-renal manifestations of TMA and the role of kidney biopsy given there was a background of advanced kidney impairment at baseline.

Original languageEnglish
Pages (from-to)688-690
Number of pages3
JournalNephrology
Volume29
Issue number10
DOIs
Publication statusPublished - 2024

Bibliographical note

Publisher Copyright:
© 2024 The Authors. Nephrology published by John Wiley & Sons Australia, Ltd on behalf of Asian Pacific Society of Nephrology.

Keywords

  • acute kidney injury
  • Alport syndrome (hereditary nephritis)
  • thrombotic microangiopathy

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