Complement-mediated thrombotic microangiopathy on a background of Alport syndrome: a case report

Craig Peter Coorey; Theo de Malmanche; Angela Chou; Martin Feddersen

doi:10.1111/nep.14305

Complement-mediated thrombotic microangiopathy on a background of Alport syndrome: a case report

Craig Peter Coorey
, Theo de Malmanche
, Angela Chou
, Martin Feddersen

Central Coast Local Health District
NSW Health Pathology
University of Newcastle
Royal North Shore Hospital

Research output: Contribution to journal › Article › peer-review

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Abstract

Here we present a case of complement-mediated thrombotic microangiopathy (TMA) in a patient who has a background of Stage 5 chronic kidney disease secondary to Alport syndrome. We explain our approach to the diagnosis of TMA, especially the reliance on non-renal manifestations of TMA and the role of kidney biopsy given there was a background of advanced kidney impairment at baseline.

Original language	English
Pages (from-to)	688-690
Number of pages	3
Journal	Nephrology
Volume	29
Issue number	10
DOIs	https://doi.org/10.1111/nep.14305
Publication status	Published - 2024

Bibliographical note

Publisher Copyright:
© 2024 The Authors. Nephrology published by John Wiley & Sons Australia, Ltd on behalf of Asian Pacific Society of Nephrology.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

acute kidney injury
Alport syndrome (hereditary nephritis)
thrombotic microangiopathy

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10.1111/nep.14305Licence: CC BY-NC-ND

Full textFinal published version, 698 KBLicence: CC BY-NC-ND

Cite this

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abstract = "Here we present a case of complement-mediated thrombotic microangiopathy (TMA) in a patient who has a background of Stage 5 chronic kidney disease secondary to Alport syndrome. We explain our approach to the diagnosis of TMA, especially the reliance on non-renal manifestations of TMA and the role of kidney biopsy given there was a background of advanced kidney impairment at baseline.",

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KW - Alport syndrome (hereditary nephritis)

KW - thrombotic microangiopathy

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Complement-mediated thrombotic microangiopathy on a background of Alport syndrome: a case report

Abstract

Bibliographical note

UN SDGs

Keywords

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