Complement-mediated thrombotic microangiopathy on a background of Alport syndrome: a case report

Craig Peter Coorey, Theo de Malmanche, Angela Chou, Martin Feddersen

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    Abstract

    Here we present a case of complement-mediated thrombotic microangiopathy (TMA) in a patient who has a background of Stage 5 chronic kidney disease secondary to Alport syndrome. We explain our approach to the diagnosis of TMA, especially the reliance on non-renal manifestations of TMA and the role of kidney biopsy given there was a background of advanced kidney impairment at baseline.
    Original languageEnglish
    Pages (from-to)688-690
    Number of pages3
    JournalNephrology
    Volume29
    Issue number10
    DOIs
    Publication statusPublished - 2024

    Bibliographical note

    Publisher Copyright:
    © 2024 The Authors. Nephrology published by John Wiley & Sons Australia, Ltd on behalf of Asian Pacific Society of Nephrology.

    Keywords

    • acute kidney injury
    • Alport syndrome (hereditary nephritis)
    • thrombotic microangiopathy

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