Computational models of pharmacological and Immunological treatment in Alzhimer's disease

Vassilis Cutsuridis; Ahmed A. Moustafa

doi:10.1002/9781119159193.ch8

Computational models of pharmacological and Immunological treatment in Alzhimer's disease

Vassilis Cutsuridis, Ahmed A. Moustafa

Western Sydney University

Research output: Chapter in Book / Conference Paper › Chapter

Abstract

Alzheimer's disease (AD) is a neurological disorder, mostly associated with cognitive decline in older age. Symptoms include episodic and semantic memory impairment, attentional deficits, and executive dysfunction. The current review summarizes prior modeling studies on treatments for Alzheimer's disease (AD), and how they impact the brain, cognition, and AD symptoms. Our paper focuses on how pharmacological medications may work, and finding better ways to treat AD.

Original language	English
Title of host publication	Computational Models of Brain and Behavior
Editors	Ahmed A. Moustafa
Place of Publication	U.S.
Publisher	Wiley & Sons
Pages	99-108
Number of pages	10
ISBN (Electronic)	9781119159193
ISBN (Print)	9781119159063
DOIs	https://doi.org/10.1002/9781119159193.ch8
Publication status	Published - 2018

Keywords

Alzheimer's disease
hippocampus (brain)
acetylcholine
amyloid
oxidative stress
computational modeling

Access to Document

10.1002/9781119159193.ch8

Cite this

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abstract = "Alzheimer's disease (AD) is a neurological disorder, mostly associated with cognitive decline in older age. Symptoms include episodic and semantic memory impairment, attentional deficits, and executive dysfunction. The current review summarizes prior modeling studies on treatments for Alzheimer's disease (AD), and how they impact the brain, cognition, and AD symptoms. Our paper focuses on how pharmacological medications may work, and finding better ways to treat AD.",

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AU - Moustafa, Ahmed A.

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AB - Alzheimer's disease (AD) is a neurological disorder, mostly associated with cognitive decline in older age. Symptoms include episodic and semantic memory impairment, attentional deficits, and executive dysfunction. The current review summarizes prior modeling studies on treatments for Alzheimer's disease (AD), and how they impact the brain, cognition, and AD symptoms. Our paper focuses on how pharmacological medications may work, and finding better ways to treat AD.

KW - Alzheimer's disease

KW - hippocampus (brain)

KW - acetylcholine

KW - amyloid

KW - oxidative stress

KW - computational modeling

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:43905

UR - http://onlinelibrary.wiley.com/doi/10.1002/9781119159193.ch8/pdf

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M3 - Chapter

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ER -

Computational models of pharmacological and Immunological treatment in Alzhimer's disease

Abstract

Keywords

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