TY - JOUR
T1 - Corneal hypoxia secondary to contact lenses
T2 - the effect of high-Dk lenses
AU - Stretton, Serina
AU - Jalbert, Isabelle
AU - Sweeney, Deborah F.
PY - 2003/9
Y1 - 2003/9
N2 - Contact lenses made from materials of low-oxygen permeability (Dk) do not meet the oxygen requirements of the cornea for overnight wear. Long-term extended wear of these lenses results in chronic changes to all layers of the cornea, many of which are associated with hypoxia. High-Dk silicone hydrogel and gas permeable lenses are now available for 30-night continuous wear. The high-oxygen transmissibilities of these lenses have enabled the development of a successful continuous wear modality by eliminating the hypoxic effects of long-term wear. Presently, the focus is on improving lens performance by developing lenses that are more biocompatible, provide greater comfort, and maintain a stable tear film without inflammatory or mechanically induced adverse events.
AB - Contact lenses made from materials of low-oxygen permeability (Dk) do not meet the oxygen requirements of the cornea for overnight wear. Long-term extended wear of these lenses results in chronic changes to all layers of the cornea, many of which are associated with hypoxia. High-Dk silicone hydrogel and gas permeable lenses are now available for 30-night continuous wear. The high-oxygen transmissibilities of these lenses have enabled the development of a successful continuous wear modality by eliminating the hypoxic effects of long-term wear. Presently, the focus is on improving lens performance by developing lenses that are more biocompatible, provide greater comfort, and maintain a stable tear film without inflammatory or mechanically induced adverse events.
UR - http://www.scopus.com/inward/record.url?scp=0141480860&partnerID=8YFLogxK
U2 - 10.1016/S0896-1549(03)00053-1
DO - 10.1016/S0896-1549(03)00053-1
M3 - Article
C2 - 14564756
AN - SCOPUS:0141480860
SN - 0896-1549
VL - 16
SP - 327
EP - 340
JO - Ophthalmology Clinics of North America
JF - Ophthalmology Clinics of North America
IS - 3
ER -