Cortical responses following simultaneous and sequential retinal neurostimulation with different return configurations

Alejandro Barriga-Rivera, John W. Morley, Nigel H. Lovell, Gregg J. Suaning

Research output: Chapter in Book / Conference PaperConference Paperpeer-review

10 Citations (Scopus)

Abstract

![CDATA[Researchers continue to develop visual prostheses towards safer and more efficacious systems. However limitations still exist in the number of stimulating channels that can be integrated. Therefore there is a need for spatial and time multiplexing techniques to provide improved performance of the current technology. In particular, bright and high-contrast visual scenes may require simultaneous activation of several electrodes. In this research, a 24-electrode array was suprachoroidally implanted in three normally-sighted cats. Multi-unit activity was recorded from the primary visual cortex. Four stimulation strategies were contrasted to provide activation of seven electrodes arranged hexagonally: simultaneous monopolar, sequential monopolar, sequential bipolar and hexapolar. Both monopolar configurations showed similar cortical activation maps. Hexapolar and sequential bipolar configurations activated a lower number of cortical channels. Overall, the return configuration played a more relevant role in cortical activation than time multiplexing and thus, rapid sequential stimulation may assist in reducing the number of channels required to activate large retinal areas.]]
Original languageEnglish
Title of host publicationProceedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC '16), 16-20 August 2016, Orlando, Florida, USA
PublisherIEEE
Pages5435-5438
Number of pages4
ISBN (Print)9781457702204
DOIs
Publication statusPublished - 2016
EventIEEE Engineering in Medicine and Biology Society. Annual Conference -
Duration: 16 Aug 2016 → …

Publication series

Name
ISSN (Print)1558-4615

Conference

ConferenceIEEE Engineering in Medicine and Biology Society. Annual Conference
Period16/08/16 → …

Keywords

  • electrodes
  • eye
  • neurophysiology
  • prosthesis
  • retina

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