@inproceedings{c790f796dd61425dbbf0de866c7798ae,
title = "Cortical responses following simultaneous and sequential retinal neurostimulation with different return configurations",
abstract = "Researchers continue to develop visual prostheses towards safer and more efficacious systems. However limitations still exist in the number of stimulating channels that can be integrated. Therefore there is a need for spatial and time multiplexing techniques to provide improved performance of the current technology. In particular, bright and high-contrast visual scenes may require simultaneous activation of several electrodes. In this research, a 24-electrode array was suprachoroidally implanted in three normally-sighted cats. Multi-unit activity was recorded from the primary visual cortex. Four stimulation strategies were contrasted to provide activation of seven electrodes arranged hexagonally: simultaneous monopolar, sequential monopolar, sequential bipolar and hexapolar. Both monopolar configurations showed similar cortical activation maps. Hexapolar and sequential bipolar configurations activated a lower number of cortical channels. Overall, the return configuration played a more relevant role in cortical activation than time multiplexing and thus, rapid sequential stimulation may assist in reducing the number of channels required to activate large retinal areas.",
keywords = "electrodes, eye, neurophysiology, prosthesis, retina",
author = "Alejandro Barriga-Rivera and Morley, {John W.} and Lovell, {Nigel H.} and Suaning, {Gregg J.}",
year = "2016",
doi = "10.1109/EMBC.2016.7591956",
language = "English",
isbn = "9781457702204",
publisher = "IEEE",
pages = "5435--5438",
booktitle = "Proceedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC '16), 16-20 August 2016, Orlando, Florida, USA",
note = "IEEE Engineering in Medicine and Biology Society. Annual Conference ; Conference date: 16-08-2016",
}