TY - JOUR
T1 - Current and potential treatments for cervical cancer
AU - Yee, Grace P.C.
AU - Souza, Paul de
AU - Khachigian, Levon M.
PY - 2013
Y1 - 2013
N2 - Cervical cancer is the third most common carcinoma in women worldwide. Despite increasing efforts to improve therapy in this disease, a significant proportion of women still die, mostly from recurrent or chemoresistant disease. This review discusses current treatments for early cervical cancer, advanced disease, and recurrent cervical cancer, and covers concurrent chemoradiation, neoadjuvant chemotherapy before surgery and radiation, single agent treatment, combination treatment, platinum-based and non-platinum based therapy. We also discuss promising therapeutic strategies for cervical cancer including targeted therapy, cell-based therapy, combined siRNA and chemotherapy, and immunotherapy.
AB - Cervical cancer is the third most common carcinoma in women worldwide. Despite increasing efforts to improve therapy in this disease, a significant proportion of women still die, mostly from recurrent or chemoresistant disease. This review discusses current treatments for early cervical cancer, advanced disease, and recurrent cervical cancer, and covers concurrent chemoradiation, neoadjuvant chemotherapy before surgery and radiation, single agent treatment, combination treatment, platinum-based and non-platinum based therapy. We also discuss promising therapeutic strategies for cervical cancer including targeted therapy, cell-based therapy, combined siRNA and chemotherapy, and immunotherapy.
UR - http://handle.uws.edu.au:8081/1959.7/530746
U2 - 10.2174/1568009611313020009
DO - 10.2174/1568009611313020009
M3 - Article
SN - 1568-0096
VL - 13
SP - 205
EP - 220
JO - Current Cancer Drug Targets
JF - Current Cancer Drug Targets
IS - 2
ER -
