Current trends in clinical genetics of colorectal cancer

Srdjan Markovic, Ivan Dimitrijevic, Branimir Zogovic, Velimir Markovic, Goran Barisic, Zoran Krivokapic

Research output: Contribution to journalArticlepeer-review

Abstract

Recent innovations in molecular biology and colorectal cancer (CRC) genetics have facilitated the understanding of the pathogenesis of sporadic and hereditary CRC syndromes. The development of technology has enabled data collection for a number of genetic factors, which lead to understanding of the molecular mechanisms underlying CRC. The incidence and the nature of CRC is a mixture of genetic and environmental factors. The current field of interest is to understand how molecular basis could shape predisposition for developing CRC, disease progression and response to chemotherapy. In this article, we summarize new and developing genetic markers, and assess their clinical value for inherited and sporadic CRC.
Original languageEnglish
Pages (from-to)1042-1049
Number of pages8
JournalJournal of Balkan Union of Oncology
Volume21
Issue number5
Publication statusPublished - 2016

Keywords

  • biochemical markers
  • colon (anatomy)

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