Cytokines, nitric oxide, heat shock proteins and virulence in Toxoplasma

C. M. D. Miller, N. C. Smith, A. M. Johnson

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)

Abstract

Elucidating the factors that play important roles in the expression of virulence by parasites is crucial to understanding disease pathogenesis and to developing control strategies rationally. Here, Kate Miller, Nick Smith and Alan Johnson, using Toxoplasma gondii as a model, argue that the interactions between the immune system and 70 kDa heat shock proteins of apicomplexan parasites profoundly influence parasite virulence.
Original languageEnglish
Pages (from-to)418-422
Number of pages5
JournalParasitology Today
Volume15
Issue number10
DOIs
Publication statusPublished - 1999

Keywords

  • Toxoplasma gondii
  • apicomplexa
  • cytokines
  • nitric oxide

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