Cytokines, nitric oxide, heat shock proteins and virulence in Toxoplasma

C. M. D. Miller; N. C. Smith; A. M. Johnson

doi:10.1016/S0169-4758(99)01515-X

Cytokines, nitric oxide, heat shock proteins and virulence in Toxoplasma

C. M. D. Miller, N. C. Smith, A. M. Johnson

Western Sydney University

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

Elucidating the factors that play important roles in the expression of virulence by parasites is crucial to understanding disease pathogenesis and to developing control strategies rationally. Here, Kate Miller, Nick Smith and Alan Johnson, using Toxoplasma gondii as a model, argue that the interactions between the immune system and 70 kDa heat shock proteins of apicomplexan parasites profoundly influence parasite virulence.

Original language	English
Pages (from-to)	418-422
Number of pages	5
Journal	Parasitology Today
Volume	15
Issue number	10
DOIs	https://doi.org/10.1016/S0169-4758(99)01515-X
Publication status	Published - 1999

Keywords

Toxoplasma gondii
apicomplexa
cytokines
nitric oxide

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10.1016/S0169-4758(99)01515-X

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title = "Cytokines, nitric oxide, heat shock proteins and virulence in Toxoplasma",

abstract = "Elucidating the factors that play important roles in the expression of virulence by parasites is crucial to understanding disease pathogenesis and to developing control strategies rationally. Here, Kate Miller, Nick Smith and Alan Johnson, using Toxoplasma gondii as a model, argue that the interactions between the immune system and 70 kDa heat shock proteins of apicomplexan parasites profoundly influence parasite virulence.",

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AU - Miller, C. M. D.

AU - Smith, N. C.

AU - Johnson, A. M.

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N2 - Elucidating the factors that play important roles in the expression of virulence by parasites is crucial to understanding disease pathogenesis and to developing control strategies rationally. Here, Kate Miller, Nick Smith and Alan Johnson, using Toxoplasma gondii as a model, argue that the interactions between the immune system and 70 kDa heat shock proteins of apicomplexan parasites profoundly influence parasite virulence.

AB - Elucidating the factors that play important roles in the expression of virulence by parasites is crucial to understanding disease pathogenesis and to developing control strategies rationally. Here, Kate Miller, Nick Smith and Alan Johnson, using Toxoplasma gondii as a model, argue that the interactions between the immune system and 70 kDa heat shock proteins of apicomplexan parasites profoundly influence parasite virulence.

KW - Toxoplasma gondii

KW - apicomplexa

KW - cytokines

KW - nitric oxide

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:40109

U2 - 10.1016/S0169-4758(99)01515-X

DO - 10.1016/S0169-4758(99)01515-X

M3 - Article

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VL - 15

SP - 418

EP - 422

JO - Parasitology Today

JF - Parasitology Today

IS - 10

ER -

Cytokines, nitric oxide, heat shock proteins and virulence in Toxoplasma

Abstract

Keywords

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