Abstract
Elucidating the factors that play important roles in the expression of virulence by parasites is crucial to understanding disease pathogenesis and to developing control strategies rationally. Here, Kate Miller, Nick Smith and Alan Johnson, using Toxoplasma gondii as a model, argue that the interactions between the immune system and 70 kDa heat shock proteins of apicomplexan parasites profoundly influence parasite virulence.
Original language | English |
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Pages (from-to) | 418-422 |
Number of pages | 5 |
Journal | Parasitology Today |
Volume | 15 |
Issue number | 10 |
DOIs | |
Publication status | Published - 1999 |
Keywords
- Toxoplasma gondii
- apicomplexa
- cytokines
- nitric oxide