Cytotoxic mechanisms of berberine-phytantriol liquid crystalline nanoparticles against non-small-cell lung cancer

Keshav Raj Paudel; Bikash Manandhar; Sachin Kumar Singh; Gaurav Gupta; Philip Michael Hansbro; Dinesh Kumar Chellappan; Kamal Dua

doi:10.17179/excli2023-6156

Cytotoxic mechanisms of berberine-phytantriol liquid crystalline nanoparticles against non-small-cell lung cancer

Keshav Raj Paudel
, Bikash Manandhar
, Sachin Kumar Singh
, Gaurav Gupta
, Philip Michael Hansbro
, Dinesh Kumar Chellappan
, Kamal Dua

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Lung cancer is the leading cause of cancer-related deaths worldwide, with 1.79 million re-ported deaths in the year 2020 alone (Thai et al., 2021). Non-small-cell lung cancer (NSCLC) makes up ~85 % of total cancer cases, making it the most prevalent form of lung cancer. To-bacco smoking, environmental pollutants and genetic predisposition are the main factors that contribute to the pathogenesis of NSCLC. The therapeutic management of NSCLC and the disease progression include surgical resection, radiotherapy, chemotherapy, and immunother-apy.

Original language	English
Pages (from-to)	516-519
Number of pages	4
Journal	EXCLI Journal
Volume	22
DOIs	https://doi.org/10.17179/excli2023-6156
Publication status	Published - 2 Jan 2023
Externally published	Yes

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SDG 3 Good Health and Well-being

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Cite this

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title = "Cytotoxic mechanisms of berberine-phytantriol liquid crystalline nanoparticles against non-small-cell lung cancer",

abstract = "Lung cancer is the leading cause of cancer-related deaths worldwide, with 1.79 million re-ported deaths in the year 2020 alone (Thai et al., 2021). Non-small-cell lung cancer (NSCLC) makes up \textasciitilde{}85 \% of total cancer cases, making it the most prevalent form of lung cancer. To-bacco smoking, environmental pollutants and genetic predisposition are the main factors that contribute to the pathogenesis of NSCLC. The therapeutic management of NSCLC and the disease progression include surgical resection, radiotherapy, chemotherapy, and immunother-apy.",

author = "Paudel, \{Keshav Raj\} and Bikash Manandhar and Singh, \{Sachin Kumar\} and Gaurav Gupta and Hansbro, \{Philip Michael\} and Chellappan, \{Dinesh Kumar\} and Kamal Dua",

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doi = "10.17179/excli2023-6156",

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T1 - Cytotoxic mechanisms of berberine-phytantriol liquid crystalline nanoparticles against non-small-cell lung cancer

AU - Paudel, Keshav Raj

AU - Manandhar, Bikash

AU - Singh, Sachin Kumar

AU - Gupta, Gaurav

AU - Hansbro, Philip Michael

AU - Chellappan, Dinesh Kumar

AU - Dua, Kamal

PY - 2023/1/2

Y1 - 2023/1/2

N2 - Lung cancer is the leading cause of cancer-related deaths worldwide, with 1.79 million re-ported deaths in the year 2020 alone (Thai et al., 2021). Non-small-cell lung cancer (NSCLC) makes up ~85 % of total cancer cases, making it the most prevalent form of lung cancer. To-bacco smoking, environmental pollutants and genetic predisposition are the main factors that contribute to the pathogenesis of NSCLC. The therapeutic management of NSCLC and the disease progression include surgical resection, radiotherapy, chemotherapy, and immunother-apy.

AB - Lung cancer is the leading cause of cancer-related deaths worldwide, with 1.79 million re-ported deaths in the year 2020 alone (Thai et al., 2021). Non-small-cell lung cancer (NSCLC) makes up ~85 % of total cancer cases, making it the most prevalent form of lung cancer. To-bacco smoking, environmental pollutants and genetic predisposition are the main factors that contribute to the pathogenesis of NSCLC. The therapeutic management of NSCLC and the disease progression include surgical resection, radiotherapy, chemotherapy, and immunother-apy.

UR - https://www.scopus.com/pages/publications/85163351071

U2 - 10.17179/excli2023-6156

DO - 10.17179/excli2023-6156

M3 - Article

SN - 1611-2156

VL - 22

SP - 516

EP - 519

JO - EXCLI Journal

JF - EXCLI Journal

ER -

Cytotoxic mechanisms of berberine-phytantriol liquid crystalline nanoparticles against non-small-cell lung cancer

Abstract

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