Denonvilliers' fascia in men : a sheet plastination and confocal microscopy study of the prerectal space and the presence of an optimal anterior plane when mobilizing the rectum for cancer

Zhaoyang Xu, Pierre H. Chapuis, Les Bokey, Ming Zhang

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Aim: The aim of this study was to investigate the detailed, in situ, morphology of Denonvilliers' fascia (DVF) in cadavers using sheet plastination and confocal microscopy and to review and describe the optimal anterior plane for mobilization of the distal rectum. Method: Six male cadavers (age range 46-87 years) were prepared as six sets of transverse (× 2), coronal (× 1) and sagittal (× 3) plastinated sections which were examined under a confocal laser scanning microscope. Results: In this study a consistent space between the anterior rectal wall and the posterior surface of the prostate and seminal vesicles above the level of the perineal body was termed the prerectal space. Within that prerectal space we identified fibres which take their origin from the external urethral sphincter (EUS), together with others from the longitudinal rectal muscle (LRM) and the connective tissue sheaths of neurovascular bundles. Neither the EUS- nor the LRM-originated fibres were continuous with the endopelvic fascia; they were interposed laterally and cranially by multiple neurovascular bundles. Further, our results suggest that the peritoneum does not descend deep within the prerectal space. Conclusion: This study reveals the undisturbed, in situ, structural detail of membrane-like structures in the prerectal space and confirms that the optimal plane for anterolateral mobilization of the rectum is posterior to the multilayered Denonvilliers' fascia.
Original languageEnglish
Pages (from-to)236-242
Number of pages25
JournalColorectal Disease
Volume20
Issue number3
DOIs
Publication statusPublished - Mar 2018

Bibliographical note

Publisher Copyright:
Colorectal Disease © 2017 The Association of Coloproctology of Great Britain and Ireland

Keywords

  • cancer
  • confocal microscopy
  • morphology
  • rectum

Fingerprint

Dive into the research topics of 'Denonvilliers' fascia in men : a sheet plastination and confocal microscopy study of the prerectal space and the presence of an optimal anterior plane when mobilizing the rectum for cancer'. Together they form a unique fingerprint.

Cite this