@inproceedings{ce0d6b2b2426495786f2bbb317eb5d42,
title = "Detecting electroporation by assessing the time constants in the exponential response of human skin to voltage controlled impulse electrical stimulation",
abstract = "We propose a new method for extracting the electrical properties of human skin based on the time constant analysis of its exponential response to impulse stimulation. As a result of this analysis an adjacent finding has arisen. We have found that stratum corneum electroporation can be detected using this analysis method. We have observed that a one time-constant model is appropriate for describing the electrical properties of human skin at low amplitude applied voltages (<30V), and a two time-constant model best describes skin electrical properties at higher amplitude applied voltages (>30V). Higher voltage amplitudes (>30V) have been proven to create pores in the skin's stratum corneum which offer a new, lower resistance, pathway for the passage of current through the skin. Our data shows that when pores are formed in the stratum corneum they can be detected, in-vivo, due to the fact that a second time constant describes current flow through them.",
author = "B{\^i}rlea, \{S{\^i}nziana I.\} and Corley, \{Gavin J.\} and B{\^i}rlea, \{Nicolae M.\} and Breen, \{Paul P.\} and Fabio Quondamatteo and Gear{\'o}id {\'O}laighin",
year = "2009",
doi = "10.1109/IEMBS.2009.5334144",
language = "English",
isbn = "9781424432967",
series = "Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009",
publisher = "IEEE Computer Society",
pages = "1355--1358",
booktitle = "Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society",
note = "31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 ; Conference date: 02-09-2009 Through 06-09-2009",
}