Development of an inexpensive and non-invasive mass spectrometry based diagnostic test for early stage atherosclerosis

Mario Fernando; Aiden O'Loughlin; David G. Harman

Development of an inexpensive and non-invasive mass spectrometry based diagnostic test for early stage atherosclerosis

Mario Fernando, Aiden O'Loughlin, David G. Harman

Western Sydney University

Research output: Chapter in Book / Conference Paper › Conference Paper

Abstract

![CDATA[Coronary artery disease (CAD) is the leading cause of death worldwide, accounting for 32% of mortality. In Australia CAD causes 45,000 deaths annually, costing the health system $8 billion per year. CAD is caused by atherosclerosis, the build-up of plaque inside arteries. Diagnosis of CAD presents several problems: it is expensive, imparts a significant radiation load to the patient, and is not sensitive enough to detect the disease in its early stages. We have developed an LC-MS/MS method which looks promising as a sensitive, specific, inexpensive and non-invasive diagnostic test for CAD at a stage where intervention will be effective.]]

Original language	English
Title of host publication	12th ACT Mass Spectrometry Symposium 2018: December 4, 2018, Australian National University
Publisher	Australian National University
Pages	16-16
Number of pages	1
Publication status	Published - 2018
Event	ACT Mass Spectrometry Symposium - Duration: 1 Jan 2018 → …

Conference

Conference	ACT Mass Spectrometry Symposium
Period	1/01/18 → …

Keywords

coronary heart disease
atherosclerosis
diagnosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

@inproceedings{d16d74cfe10f4f1a8335f93dadf2f34b,

title = "Development of an inexpensive and non-invasive mass spectrometry based diagnostic test for early stage atherosclerosis",

abstract = "![CDATA[Coronary artery disease (CAD) is the leading cause of death worldwide, accounting for 32% of mortality. In Australia CAD causes 45,000 deaths annually, costing the health system $8 billion per year. CAD is caused by atherosclerosis, the build-up of plaque inside arteries. Diagnosis of CAD presents several problems: it is expensive, imparts a significant radiation load to the patient, and is not sensitive enough to detect the disease in its early stages. We have developed an LC-MS/MS method which looks promising as a sensitive, specific, inexpensive and non-invasive diagnostic test for CAD at a stage where intervention will be effective.]]",

keywords = "coronary heart disease, atherosclerosis, diagnosis",

author = "Mario Fernando and Aiden O'Loughlin and Harman, {David G.}",

year = "2018",

language = "English",

pages = "16--16",

booktitle = "12th ACT Mass Spectrometry Symposium 2018: December 4, 2018, Australian National University",

publisher = "Australian National University",

note = "ACT Mass Spectrometry Symposium ; Conference date: 01-01-2018",

}

Development of an inexpensive and non-invasive mass spectrometry based diagnostic test for early stage atherosclerosis. / Fernando, Mario; O'Loughlin, Aiden ; Harman, David G.
12th ACT Mass Spectrometry Symposium 2018: December 4, 2018, Australian National University. Australian National University, 2018. p. 16-16.

Research output: Chapter in Book / Conference Paper › Conference Paper

TY - GEN

T1 - Development of an inexpensive and non-invasive mass spectrometry based diagnostic test for early stage atherosclerosis

AU - Fernando, Mario

AU - O'Loughlin, Aiden

AU - Harman, David G.

PY - 2018

Y1 - 2018

N2 - ![CDATA[Coronary artery disease (CAD) is the leading cause of death worldwide, accounting for 32% of mortality. In Australia CAD causes 45,000 deaths annually, costing the health system $8 billion per year. CAD is caused by atherosclerosis, the build-up of plaque inside arteries. Diagnosis of CAD presents several problems: it is expensive, imparts a significant radiation load to the patient, and is not sensitive enough to detect the disease in its early stages. We have developed an LC-MS/MS method which looks promising as a sensitive, specific, inexpensive and non-invasive diagnostic test for CAD at a stage where intervention will be effective.]]

AB - ![CDATA[Coronary artery disease (CAD) is the leading cause of death worldwide, accounting for 32% of mortality. In Australia CAD causes 45,000 deaths annually, costing the health system $8 billion per year. CAD is caused by atherosclerosis, the build-up of plaque inside arteries. Diagnosis of CAD presents several problems: it is expensive, imparts a significant radiation load to the patient, and is not sensitive enough to detect the disease in its early stages. We have developed an LC-MS/MS method which looks promising as a sensitive, specific, inexpensive and non-invasive diagnostic test for CAD at a stage where intervention will be effective.]]

KW - coronary heart disease

KW - atherosclerosis

KW - diagnosis

UR - http://handle.westernsydney.edu.au:8081/1959.7/uws:49852

M3 - Conference Paper

SP - 16

EP - 16

BT - 12th ACT Mass Spectrometry Symposium 2018: December 4, 2018, Australian National University

PB - Australian National University

T2 - ACT Mass Spectrometry Symposium

Y2 - 1 January 2018

ER -

Development of an inexpensive and non-invasive mass spectrometry based diagnostic test for early stage atherosclerosis

Abstract

Conference

Keywords

UN SDGs

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