Diffusion-based studies on the self-stacking and nanorod formation of platinum(II) intercalators

S. Y. Kwun; Nial J. Wheate; William S. Price; Janice Aldrich-Wright

doi:10.1039/b820584a

Diffusion-based studies on the self-stacking and nanorod formation of platinum(II) intercalators

S. Y. Kwun
, Nial J. Wheate
, William S. Price
, Janice Aldrich-Wright

School of Science

Research output: Contribution to journal › Article

22 Citations (Scopus)

Abstract

Pulsed gradient spin-echo nuclear magnetic resonance diffusion measurements have been used to show that platinum(II)-based intercalating agents self-stack in solution and form nanorods 0.45-3.9 nm in length (at 25 mM); their lengths are dependent on metal complex concentration, salt concentration and solution temperature.

Original language	English
Pages (from-to)	1210-1212
Number of pages	3
Journal	Chemical Communications
Volume	10
Issue number	10
DOIs	https://doi.org/10.1039/b820584a
Publication status	Published - 2009

Keywords

DNA
antineoplastic agents
cancer
diffusion
drug delivery devices
nanorods
nuclear magnetic resonance
platinum(II)-based complexes

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10.1039/b820584a

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abstract = "Pulsed gradient spin-echo nuclear magnetic resonance diffusion measurements have been used to show that platinum(II)-based intercalating agents self-stack in solution and form nanorods 0.45-3.9 nm in length (at 25 mM); their lengths are dependent on metal complex concentration, salt concentration and solution temperature.",

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AU - Price, William S.

AU - Aldrich-Wright, Janice

PY - 2009

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AB - Pulsed gradient spin-echo nuclear magnetic resonance diffusion measurements have been used to show that platinum(II)-based intercalating agents self-stack in solution and form nanorods 0.45-3.9 nm in length (at 25 mM); their lengths are dependent on metal complex concentration, salt concentration and solution temperature.

KW - DNA

KW - antineoplastic agents

KW - cancer

KW - diffusion

KW - drug delivery devices

KW - nanorods

KW - nuclear magnetic resonance

KW - platinum(II)-based complexes

UR - http://handle.uws.edu.au:8081/1959.7/496542

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DO - 10.1039/b820584a

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JO - Chemical Communications

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ER -

Diffusion-based studies on the self-stacking and nanorod formation of platinum(II) intercalators

Abstract

Keywords

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